来自纤维素链霉菌的β-内酰胺酶编码基因的序列。
Sequence of a gene encoding beta-lactamase from Streptomyces cellulosae.
作者信息
Ogawara H
机构信息
Department of Biochemistry, Meiji College of Pharmacy, Tokyo, Japan.
出版信息
Gene. 1993 Feb 14;124(1):111-4. doi: 10.1016/0378-1119(93)90769-y.
PMID:7916705
Abstract
The nucleotide sequence of beta-lactamase (Bla)-encoding gene, bla, from Streptomyces cellulosae KCCS0127 was determined. The deduced amino acid sequence was very close to that of class-A Bla, especially those from Streptomyces species, but completely different from class-D Bla. This is contrary to the result expected from its substrate specificity and its property of binding blue dextran and NADP+.
摘要
测定了纤维链霉菌KCCS0127中β-内酰胺酶（Bla）编码基因bla的核苷酸序列。推导的氨基酸序列与A类Bla非常接近，尤其是来自链霉菌属物种的那些，但与D类Bla完全不同。这与根据其底物特异性以及结合蓝色葡聚糖和NADP⁺的特性所预期的结果相反。
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