Colombo M, Gross C G
Department of Psychology, Princeton University.
Behav Neurosci. 1994 Jun;108(3):443-55. doi: 10.1037//0735-7044.108.3.443.
Single-unit activity was recorded from inferior temporal (IT) cortex and the hippocampus in 2 macaques trained on auditory-visual and visual-visual delayed matching-to-sample tasks. The main purpose of the study was to compare the response properties of delay neurons between the 2 areas. The authors noted that (a) IT cortex delay activity was usually selective to a particular stimulus, whereas hippocampal delay activity was usually nonselective; (b) the level of delay activity was generally larger in the hippocampus than in IT cortex; and (c) unlike IT cortex delay activity, hippocampal delay activity tended to increase in magnitude as the delay progressed. The authors also examined the functional significance of delay activity and noted a higher probability of encountering a delay neuron when the monkeys were performing 75%-100% correct as compared with 50%-75% correct. The significance of these findings for visual recognition memory is discussed.
在2只经听觉-视觉和视觉-视觉延迟匹配样本任务训练的猕猴中，记录了颞下（IT）皮质和海马体的单神经元活动。该研究的主要目的是比较这两个区域中延迟神经元的反应特性。作者指出：（a）IT皮质延迟活动通常对特定刺激具有选择性，而海马体延迟活动通常是非选择性的；（b）海马体中的延迟活动水平通常比IT皮质中的更高；（c）与IT皮质延迟活动不同，海马体延迟活动的幅度倾向于随着延迟的进行而增加。作者还研究了延迟活动的功能意义，并指出与正确率为50%-75%相比，当猴子正确率为75%-100%时遇到延迟神经元的概率更高。讨论了这些发现对视觉识别记忆的意义。
