• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

酵母中细胞周期调控的转录

Cell cycle regulated transcription in yeast.

作者信息

Koch C, Nasmyth K

机构信息

Institute of Molecular Pathology, Vienna, Austria.

出版信息

Curr Opin Cell Biol. 1994 Jun;6(3):451-9. doi: 10.1016/0955-0674(94)90039-6.

DOI:10.1016/0955-0674(94)90039-6
PMID:7917338
Abstract

At least four different classes of cell cycle regulated gene exist in yeast: G1 cyclins and DNA synthesis genes are expressed in late G1; histone genes in S phase; genes for transcription factors, cell cycle regulators and replication initiation proteins in G2; and genes needed for cell separation as cells enter G1. Early and late G1-specific transcription is mediated by the Swi5/Ace2 and Swi4/Swi6 classes of factor, respectively. Changes in cyclin/Cdc28 kinases may be involved in all classes of regulation. Transcriptional control of cyclin genes has an important role in regulating cell cycle progression.

摘要

酵母中至少存在四类受细胞周期调控的基因

G1 期周期蛋白和 DNA 合成基因在 G1 晚期表达；组蛋白基因在 S 期表达；转录因子、细胞周期调节因子和复制起始蛋白的基因在 G2 期表达；而细胞进入 G1 期时细胞分离所需的基因表达。G1 早期和晚期特异性转录分别由 Swi5/Ace2 和 Swi4/Swi6 类因子介导。周期蛋白/Cdc28 激酶的变化可能参与所有类型的调控。周期蛋白基因的转录控制在调节细胞周期进程中起着重要作用。

相似文献

1
Cell cycle regulated transcription in yeast.酵母中细胞周期调控的转录
Curr Opin Cell Biol. 1994 Jun;6(3):451-9. doi: 10.1016/0955-0674(94)90039-6.
2
Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2.在酵母细胞周期中开启和关闭转录：Cln/Cdc28激酶在起始点激活结合的转录因子SBF（Swi4/Swi6），而Clb/Cdc28激酶在G2期将其从启动子上置换下来。
Genes Dev. 1996 Jan 15;10(2):129-41. doi: 10.1101/gad.10.2.129.
3
Mutational analysis of a DNA sequence involved in linking gene expression to the cell cycle.对涉及将基因表达与细胞周期相联系的DNA序列进行突变分析。
Biochem Cell Biol. 1992 Oct-Nov;70(10-11):1073-80. doi: 10.1139/o92-152.
4
The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast.SWI4和SWI6在酵母中G1期细胞周期蛋白活性中的作用。
Cell. 1991 Sep 6;66(5):995-1013. doi: 10.1016/0092-8674(91)90444-4.
5
The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.转录因子Swi5调节细胞周期蛋白激酶抑制剂p40SIC1的表达。
Mol Cell Biol. 1996 Oct;16(10):5701-7. doi: 10.1128/MCB.16.10.5701.
6
Rme1, which controls CLN2 expression in Saccharomyces cerevisiae, is a nuclear protein that is cell cycle regulated.Rme1是一种在酿酒酵母中控制CLN2表达的核蛋白，其表达受细胞周期调控。
Mol Genet Genomics. 2001 Nov;266(3):374-84. doi: 10.1007/s004380100515.
7
Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins.帮助酵母细胞周期时钟运转的机制：G2 细胞周期蛋白通过转录激活 G2 细胞周期蛋白并抑制 G1 细胞周期蛋白。
Cell. 1993 Sep 24;74(6):993-1007. doi: 10.1016/0092-8674(93)90722-3.
8
Multiple SWI6-dependent cis-acting elements control SWI4 transcription through the cell cycle.多个依赖SWI6的顺式作用元件通过细胞周期控制SWI4转录。
Mol Cell Biol. 1993 Jun;13(6):3792-801. doi: 10.1128/mcb.13.6.3792-3801.1993.
9
EGT2 gene transcription is induced predominantly by Swi5 in early G1.EGT2基因转录主要在G1早期由Swi5诱导。
Mol Cell Biol. 1996 Jul;16(7):3264-74. doi: 10.1128/MCB.16.7.3264.
10
Binding to the yeast SwI4,6-dependent cell cycle box, CACGAAA, is cell cycle regulated in vivo.与酵母中依赖于SwI4,6的细胞周期框CACGAAA的结合在体内受细胞周期调控。
Nucleic Acids Res. 1996 Feb 15;24(4):558-65. doi: 10.1093/nar/24.4.558.

引用本文的文献

1
Inferring cell cycle phases from a partially temporal network of protein interactions.从部分时间蛋白互作网络推断细胞周期相位。
Cell Rep Methods. 2023 Feb 1;3(2):100397. doi: 10.1016/j.crmeth.2023.100397. eCollection 2023 Feb 27.
2
A continuous-time stochastic Boolean model provides a quantitative description of the budding yeast cell cycle.一个连续时间随机布尔模型为芽殖酵母细胞周期提供了一个定量描述。
Sci Rep. 2022 Nov 24;12(1):20302. doi: 10.1038/s41598-022-24302-6.
3
Dilution and titration of cell-cycle regulators may control cell size in budding yeast.
细胞周期调控因子的稀释和滴定可能控制出芽酵母的细胞大小。
PLoS Comput Biol. 2018 Oct 24;14(10):e1006548. doi: 10.1371/journal.pcbi.1006548. eCollection 2018 Oct.
4
Cell cycle-regulated transcription: effectively using a genomics toolbox.细胞周期调控转录：有效运用基因组学工具包
Methods Mol Biol. 2014;1170:3-27. doi: 10.1007/978-1-4939-0888-2_1.
5
Functional studies of the yeast med5, med15 and med16 mediator tail subunits.酵母 Med5、Med15 和 Med16 中介体尾部亚基的功能研究。
PLoS One. 2013 Aug 22;8(8):e73137. doi: 10.1371/journal.pone.0073137. eCollection 2013.
6
Identification of yeast cell cycle regulated genes based on genomic features.基于基因组特征鉴定酵母细胞周期调控基因。
BMC Syst Biol. 2013 Jul 29;7:70. doi: 10.1186/1752-0509-7-70.
7
Passing messages between biological networks to refine predicted interactions.在生物网络之间传递信息以完善预测的相互作用。
PLoS One. 2013 May 31;8(5):e64832. doi: 10.1371/journal.pone.0064832. Print 2013.
8
Phosphate-activated cyclin-dependent kinase stabilizes G1 cyclin to trigger cell cycle entry.磷酸化激活的周期蛋白依赖性激酶稳定 G1 周期蛋白以触发细胞周期进入。
Mol Cell Biol. 2013 Apr;33(7):1273-84. doi: 10.1128/MCB.01556-12. Epub 2013 Jan 22.
9
Stochastic simulation for the inference of transcriptional control network of yeast cyclins genes.酵母细胞周期蛋白基因转录调控网络推断的随机模拟。
Nucleic Acids Res. 2012 Aug;40(15):7096-103. doi: 10.1093/nar/gks440. Epub 2012 May 15.
10
Regulation of histone gene expression in budding yeast.酿酒酵母中组蛋白基因表达的调控。
Genetics. 2012 May;191(1):7-20. doi: 10.1534/genetics.112.140145.