Cornu C, Cochat P, Collet J P, Delair S, Haugh M C, Rolland C
Unité de Néphrologie Pédiatrique, Hôpital Edourard Herriot, Lyon, France.
Pediatr Nephrol. 1994 Jun;8(3):275-7. doi: 10.1007/BF00866331.
Although urinary tract infections are of particular concern in young children, as they may lead to permanent health problems, there is no consensus for their acute management. We carried out a mailed survey of 455 general practitioners, 143 paediatricians (randomly selected from a list of physicians in the Rhône-Alpes region of France) and 45 paediatric nephrologists (all the members of the "Société de Néphrologie Pédiatrique") to examine their attitudes to the management of a fictitious case of a young girl with symptoms indicative of acute pyelonephritis. The responses given by the general practitioners and paediatricians were similar, whereas those given by the paediatric were similar, whereas those given by the paediatric nephrologists were often different, for example 20% of the general practitioners and 17% of the paediatricians said they would hospitalize the child, compared with 69% of the paediatric nephrologists. The majority of the general practitioners and paediatricians favoured single oral antibiotic therapy, whereas the paediatric nephrologists were split between single and combined antibiotic therapy, but preferred intravenous administration. The most frequently prescribed drug was a penicillin. The heterogeneity of the results from this survey stresses the need for the assessment of various strategies in terms of their efficacy for preventing kidney scarring and their risk-to-benefit ratios in well-designed randomised controlled trials.
尽管尿路感染在幼儿中尤为令人担忧,因为它们可能导致永久性健康问题,但对于其急性处理尚无共识。我们对455名全科医生、143名儿科医生(从法国罗纳-阿尔卑斯地区的医生名单中随机抽取)和45名儿科肾病专家(“儿科肾病学会”的所有成员)进行了邮寄调查,以了解他们对一名有急性肾盂肾炎症状的虚构小女孩病例处理的态度。全科医生和儿科医生给出的回答相似,而儿科肾病专家的回答往往不同,例如,20%的全科医生和17%的儿科医生表示他们会让孩子住院,相比之下,儿科肾病专家的这一比例为69%。大多数全科医生和儿科医生倾向于单一口服抗生素治疗,而儿科肾病专家在单一和联合抗生素治疗之间存在分歧,但更倾向于静脉给药。最常开具的药物是青霉素。这项调查结果的异质性强调了在精心设计的随机对照试验中,需要根据预防肾瘢痕形成的疗效及其风险效益比来评估各种策略。