Edwards E B, Guo T, Breen T J, Bowen G R, Daily O P
United Network Organ Sharing, Richmond, Virginia.
Clin Transpl. 1993:71-83.
Based on data from the OPTN Waiting List and the Scientific Registry between 1988 and 1992: 1. On October 31, 1993 the combined waiting list for a solid organ transplant contained 32,603 registrations. This represents more than a 100% increase since 1988. Specifically, registrations for a lung transplant grew by more than 1600% and registrations for a liver transplant increased by 356% during the period. The intestine waiting list contained 900 registrations on October 31, 1993. 2. The distribution of patient characteristics on the waiting list snapshot as of October 31, 1993 was not markedly different from that on previous snapshots. Slight increases in the percentage of older (65 years) kidney, liver, and heart registrants were apparent. A slight decrease in the percentage of highly sensitized (PRA > or = 80%) kidney registrants was observed. 3. In general, median waiting times to transplant have increased each year between 1988 and 1992. During this period, the most significant increases were observed for kidney-pancreas registrants (277% increase) and lung registrants (205% increase). 4. For all waiting lists except heart-lung, registrants with blood type O waited substantially longer for a transplant than registrants with blood type A. This was especially true for kidney registrants. Other notable differences in waiting times on the kidney waiting list occurred between Blacks and Whites and between adults and pediatric registrants. Males waited on the heart waiting list for a transplant over twice as long as females. 5. The overall percentage of registrants who died while waiting for a transplant in 1992 was 5.8%, compared with 5.5% in 1988. The highest death rates occurred for thoracic registrants (13.1%, 16.2%, and 12.7% for heart, heart-lung, and lung, respectively). The lowest death rates occurred for kidney (3.5%) and kidney-pancreas registrants (1.2%). The death rate for pancreas registrants (9.4%) was greater than the death rate for liver registrants (8.5%). The number who died while waiting increased each year between 1988 and 1992, but the rate of increase may be declining.
基于器官共享联合网络(OPTN)等待名单和科学注册中心1988年至1992年的数据:1. 1993年10月31日,实体器官移植的联合等待名单上有32,603个注册记录。这比1988年增长了100%以上。具体而言,在此期间,肺移植的注册记录增长了1600%以上,肝移植的注册记录增加了356%。1993年10月31日,肠移植等待名单上有900个注册记录。2. 截至1993年10月31日的等待名单快照中患者特征的分布与之前的快照没有明显差异。65岁及以上的肾、肝和心脏移植注册者的百分比略有增加。高敏(PRA≥80%)肾移植注册者的百分比略有下降。3. 总体而言,1988年至1992年期间,移植的中位等待时间每年都在增加。在此期间,肾胰腺移植注册者(增加277%)和肺移植注册者(增加205%)的等待时间增加最为显著。4. 除心肺移植外,所有等待名单中,O型血的注册者等待移植的时间比A型血的注册者长得多。肾移植注册者尤其如此。肾移植等待名单上的其他显著等待时间差异发生在黑人和白人之间以及成人和儿童注册者之间。男性在心脏移植等待名单上的等待时间是女性的两倍多。5. 1992年等待移植期间死亡的注册者总体百分比为5.8%,而1988年为5.5%。胸科移植注册者的死亡率最高(心脏、心肺和肺移植分别为13.1%、16.2%和12.7%)。肾移植(3.5%)和肾胰腺移植注册者(1.2%)的死亡率最低。胰腺移植注册者的死亡率(9.4%)高于肝移植注册者(8.5%)。1988年至1992年期间,等待期间死亡的人数逐年增加,但增长速度可能在下降。