免疫抑制药物对细胞介导免疫的体外相关指标的影响。迁移抑制试验。
Effect of immunosuppressive drugs on an in vito correlate of cell-mediated immunity. The migration inhibition test.
作者信息
Pekárek J, Svejcar J, Nouza K, Johanovsky J
出版信息
Immunology. 1976 Nov;31(5):773-9.
Abstract
The effect of a number of immunosuppressive drugs on the migration-inhibition test was studied. These drugs could be divided into four categories: (1) drugs influencing both the MIF production and MIF effect on macrophages (amethopterin, azathioprine); (2) drugs influencing MIF production (puromycin, actinomycin D); (3) drugs influencing the effect of MIF on macrophages (hydrocortisone); (4) drugs without any influence.
摘要
研究了多种免疫抑制药物对迁移抑制试验的影响。这些药物可分为四类：（1）影响巨噬细胞移动抑制因子（MIF）产生及MIF对巨噬细胞作用的药物（氨甲蝶呤、硫唑嘌呤）；（2）影响MIF产生的药物（嘌呤霉素、放线菌素D）；（3）影响MIF对巨噬细胞作用的药物（氢化可的松）；（4）无任何影响的药物。
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