迟发型超敏反应中的淋巴细胞。3. X射线辐射对被动转移及可溶性介质体外产生的影响。
Lymphoid cells in delayed hypersensitivity. 3. The influence of x-irradiation on passive transfer and on in vitro production of soluble mediators.
作者信息
Salvin S B, Nishio J
出版信息
J Exp Med. 1972 Apr 1;135(4):985-96. doi: 10.1084/jem.135.4.985.
Abstract
X-irradiation up to 480 R does not inhibit either adoptive transfer of delayed hypersensitivity or production in vitro of soluble mediators, such as migration-inhibitory factor (MIF). Above that dosage and as high as 3000 R, adoptive transfer is inhibited, but production of MIF is not. An increase in skin response occurred when 24-48 hr were allowed to elapse after intravenous transfer and before skin testing. Treatment of recipients with colchicine at the time of adoptive transfer inhibited the development of a skin reaction to specific antigen.
摘要
高达480伦琴的X射线照射既不抑制迟发型超敏反应的过继转移，也不抑制体外可溶性介质如迁移抑制因子（MIF）的产生。高于该剂量直至3000伦琴，过继转移受到抑制，但MIF的产生不受影响。静脉注射后24至48小时再进行皮肤试验时，皮肤反应增强。在过继转移时用秋水仙碱处理受体可抑制对特异性抗原的皮肤反应的发展。
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本文引用的文献
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