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对随机抽取的居家老年人样本中贫血患病率的描述性分析:一项意大利多中心研究的部分结果。

Descriptive analysis of the prevalence of anemia in a randomly selected sample of elderly people living at home: some results of an Italian multicentric study.

作者信息

Inelmen E M, D'Alessio M, Gatto M R, Baggio M B, Jimenez G, Bizzotto M G, Enzi G

机构信息

Department of Internal Medicine, University of Padova, Italy.

出版信息

Aging (Milano). 1994 Apr;6(2):81-9. doi: 10.1007/BF03324220.

Abstract

We studied hematological indexes (RBC, HB, HT, MCV), serum iron and serum ferritin values in 1784 randomly selected subjects aged 65 and over (725 males and 1059 females) divided into five age groups (65-69, 70-74, 75-79, 80-84, > or = 85 years). The subjects were classified as anemic and normochromic according to the criteria for a "geriatric" level of anemia (HB < or = 12 g/dL in both sexes) as well as "W.H.O." levels for anemia (HB < 13 g/dL in males and < 12 g/dL in females). Macrocytosis (MCV > 100 fl) and low serum ferritin level (< or = 12 ng/dL) were classified according to MCV and serum ferritin values. Mean HB values in males were 14.85 +/- 1.33; 14.82 +/- 1.40; 14.77 +/- 1.43; 14.59 +/- 1.47 and 13.83 +/- 1.13 in the five age groups (65-69, 70-74, 75-79, 80-84 and > or = 85 years) respectively; in females, they were 13.77 +/- 1.15; 13.75 +/- 1.27; 13.44 +/- 1.39; 13.44 +/- 1.52 and 13.34 +/- 1.61, respectively. There was a low frequency of anemia in the entire sample: 2.9% in males and 9.9% in females according to the "geriatric" level, and 9.4% in males and 8.8% in females according to the "W.H.O." level. There was a higher prevalence of macrocytosis in males (6.3%) than in females (3.3%). We conclude that red cell parameters tend to decrease in aging, and further investigations are needed that exclude persons with existing chronic conditions, and incorporate data on nutritional status.

摘要

我们研究了1784名随机选取的65岁及以上受试者(725名男性和1059名女性)的血液学指标(红细胞、血红蛋白、红细胞压积、平均红细胞体积)、血清铁和血清铁蛋白值,这些受试者被分为五个年龄组(65 - 69岁、70 - 74岁、75 - 79岁、80 - 84岁、≥85岁)。根据“老年”贫血标准(男女血红蛋白均≤12 g/dL)以及世界卫生组织(W.H.O.)贫血标准(男性血红蛋白<13 g/dL,女性血红蛋白<12 g/dL),将受试者分为贫血组和正常色素组。根据平均红细胞体积和血清铁蛋白值对大细胞性贫血(平均红细胞体积>100 fl)和低血清铁蛋白水平(≤12 ng/dL)进行分类。五个年龄组(65 - 69岁、70 - 74岁、75 - 79岁、80 - 84岁、≥85岁)男性的平均血红蛋白值分别为14.85±1.33、14.82±1.40、14.77±1.43、14.59±1.47和13.83±1.13;女性的平均血红蛋白值分别为13.77±1.15、14.75±1.27、13.44±1.39、13.44±1.52和13.34±1.61。整个样本中贫血发生率较低:按照“老年”标准,男性为2.9%,女性为9.9%;按照世界卫生组织标准,男性为9.4%,女性为8.8%。男性大细胞性贫血的患病率(6.3%)高于女性(3.3%)。我们得出结论,红细胞参数在衰老过程中趋于下降,需要进一步开展研究,排除患有现有慢性病的人群,并纳入营养状况数据。

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