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405例老年患者贫血的病因分析

An etiologic profile of anemia in 405 geriatric patients.

作者信息

Geisel Tabea, Martin Julia, Schulze Bettina, Schaefer Roland, Bach Matthias, Virgin Garth, Stein Jürgen

机构信息

Crohn Colitis Center Rhein-Main, 60594 Frankfurt/Main, Germany ; Institute of Nutritional Science, University of Giessen, 35392 Giessen, Germany.

St. Elisabethen Krankenhaus, 60487 Frankfurt/Main, Germany.

出版信息

Anemia. 2014;2014:932486. doi: 10.1155/2014/932486. Epub 2014 Feb 23.

Abstract

Background. Anemia is a common condition in the elderly and a significant risk factor for increased morbidity and mortality, reducing not only functional capacity and mobility but also quality of life. Currently, few data are available regarding anemia in hospitalized geriatric patients. Our retrospective study investigated epidemiology and causes of anemia in 405 hospitalized geriatric patients. Methods. Data analysis was performed using laboratory parameters determined during routine hospital admission procedures (hemoglobin, ferritin, transferrin saturation, C-reactive protein, vitamin B12, folic acid, and creatinine) in addition to medical history and demographics. Results. Anemia affected approximately two-thirds of subjects. Of 386 patients with recorded hemoglobin values, 66.3% were anemic according to WHO criteria, mostly (85.1%) in a mild form. Anemia was primarily due to iron deficiency (65%), frequently due to underlying chronic infection (62.1%), or of mixed etiology involving a combination of chronic disease and iron deficiency, with absolute iron deficiency playing a comparatively minor role. Conclusion. Greater awareness of anemia in the elderly is warranted due to its high prevalence and negative effect on outcomes, hospitalization duration, and mortality. Geriatric patients should be routinely screened for anemia and etiological causes of anemia individually assessed to allow timely initiation of appropriate therapy.

摘要

背景。贫血是老年人的常见病症,也是发病率和死亡率增加的重要危险因素,不仅会降低功能能力和活动能力,还会影响生活质量。目前,关于住院老年患者贫血情况的数据较少。我们的回顾性研究调查了405例住院老年患者贫血的流行病学情况及病因。方法。除病史和人口统计学资料外,还使用常规住院程序中测定的实验室参数(血红蛋白、铁蛋白、转铁蛋白饱和度、C反应蛋白、维生素B12、叶酸和肌酐)进行数据分析。结果。约三分之二的受试者受贫血影响。在386例记录了血红蛋白值的患者中,根据世界卫生组织标准,66.3%的患者贫血,其中大多数(85.1%)为轻度贫血。贫血主要归因于缺铁(65%),常因潜在的慢性感染(62.1%),或病因混合,涉及慢性病和缺铁的组合,绝对缺铁起的作用相对较小。结论。鉴于贫血在老年人中患病率高且对预后、住院时间和死亡率有负面影响,有必要提高对其的认识。应定期对老年患者进行贫血筛查,并对贫血的病因进行单独评估,以便及时开始适当的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7cd/3953485/059afa1cac16/ANEMIA2014-932486.001.jpg

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