磷酸烯醇式丙酮酸：葡萄糖磷酸转移酶系统缺陷的3-脱氧-3-氟-D-葡萄糖抗性鼠伤寒沙门氏菌突变体
3-Deoxy-3-fluoro-D-glucose-resistant Salmonella typhimurium mutants defective in the phosphoenolpyruvate:glycose phosphotransferase system.
作者信息
Melton T, Kundig W, Hartman P E, Meadow N
出版信息
J Bacteriol. 1976 Dec;128(3):794-800. doi: 10.1128/jb.128.3.794-800.1976.
Abstract
Three classes of phosphotransferase system mutants in Salmonella typhimurium were selected through their resistance to 3-deoxy-3-fluoro-D-glucose (DFG). Strains with mutations in the ptsH (HPr) and/or pts I (enzyme I) genes were selected on medium containing lactate plus DFG. Strains with mutations in ptsH but not pstI were selected on medium containing fructose plus DFG. Clones isolated from fructose plus DFG semisolid plates and selected for ability to swarm were mutant in either ptsH or ptsG. Mutants of the latter class were defective in enzyme IIB', a membrane component of the glucose transport system. Some pleiotropic properties of one representative ptsG mutant are described.
摘要
通过对鼠伤寒沙门氏菌的磷酸转移酶系统突变体进行对3-脱氧-3-氟-D-葡萄糖（DFG）的抗性筛选，选出了三类突变体。ptsH（HPr）和/或ptsI（酶I）基因发生突变的菌株是在含有乳酸盐加DFG的培养基上筛选出来的。ptsH发生突变但pstI未突变的菌株是在含有果糖加DFG的培养基上筛选出来的。从果糖加DFG半固体平板上分离并选择具有群体运动能力的克隆，其ptsH或ptsG发生了突变。后一类突变体在酶IIB'（葡萄糖转运系统的膜成分）中存在缺陷。描述了一个代表性ptsG突变体的一些多效性特征。
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本文引用的文献
1
Genetic control of glucose uptake by Escherichia coli.大肠杆菌对葡萄糖摄取的遗传控制。
FEBS Lett. 1972 Feb 15;20(3):270-272. doi: 10.1016/0014-5793(72)80084-x.
2
Metabolism of 3-deoxy-3-fluoro-D-glucose by Pseudomonas fluorescens.荧光假单胞菌对3-脱氧-3-氟-D-葡萄糖的代谢
FEBS Lett. 1970 Dec 11;11(4):268-272. doi: 10.1016/0014-5793(70)80545-2.
3
The effect of 3-deoxy-3-fluoro-d-glucose on Saccharomyces cerevisiae.3-脱氧-3-氟-D-葡萄糖对酿酒酵母的作用。
Biochem J. 1969 Sep;114(2):445-7. doi: 10.1042/bj1140445.
4
Sugar transport. II. Characterization of constitutive membrane-bound enzymes II of the Escherichia coli phosphotransferase system.糖转运。二。大肠杆菌磷酸转移酶系统组成型膜结合酶II的特性
J Biol Chem. 1971 Mar 10;246(5):1407-18.
5
A sodium-dependent sugar co-transport system in bacteria.细菌中的一种钠依赖性糖共转运系统。
Biochem Biophys Res Commun. 1971 Jul 2;44(1):132-8. doi: 10.1016/s0006-291x(71)80168-7.
6
Evidence that the inducible phosphoenolpyruvate:D-fructose 1-phosphotransferase system of Aerobacter aerogenes does not require "HPr".产气气杆菌的诱导型磷酸烯醇丙酮酸：D-果糖1-磷酸转移酶系统不需要“HPr”的证据。
Biochem Biophys Res Commun. 1973 May 1;52(1):93-7. doi: 10.1016/0006-291x(73)90958-3.
7
Promoter-like mutation affecting HPr and enzyme I of the phosphoenolpyruvate: sugar phosphotransferase system in Salmonella typhimurium.影响鼠伤寒沙门氏菌磷酸烯醇丙酮酸：糖磷酸转移酶系统中HPr和酶I的启动子样突变
J Bacteriol. 1974 Oct;120(1):245-52. doi: 10.1128/jb.120.1.245-252.1974.
8
Inhibition by 3-deoxy-3-fluoro-D-glucose of the utilization of lactose and other carbon sources by Escherichia coli.3-脱氧-3-氟-D-葡萄糖对大肠杆菌利用乳糖及其他碳源的抑制作用。
J Gen Microbiol. 1973 Jun;76(2):305-18. doi: 10.1099/00221287-76-2-305.
9
Deletion mapping of the genes coding for HPr and enzyme I of the phosphoenolpyruvate: sugar phosphotransferase system in Salmonella typhimurium.鼠伤寒沙门氏菌中磷酸烯醇丙酮酸：糖磷酸转移酶系统的HPr和酶I编码基因的缺失定位
J Bacteriol. 1972 Oct;112(1):17-29. doi: 10.1128/jb.112.1.17-29.1972.
10
Molecular interactions in the bacterial phosphoenolpyruvate-phosphotransferase system (PTS).细菌磷酸烯醇式丙酮酸-磷酸转移酶系统（PTS）中的分子相互作用。
J Supramol Struct. 1974;2(5-6):695-814. doi: 10.1002/jss.400020514.
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