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体外循环手术期间的血细胞比容测量:三种即时检验方法与血细胞计数器的比较

Haematocrit measurements during cardiopulmonary bypass surgery: comparison of three stat methods with a blood cell counter.

作者信息

al-Odeh A, Varga Z A, Angelin G D

机构信息

Department of Cardiac Surgery, University of Bristol, Bristol Royal Infirmary, UK.

出版信息

Perfusion. 1994 Mar;9(2):127-34. doi: 10.1177/026765919400900207.

DOI:10.1177/026765919400900207
PMID:7919598
Abstract

Monitoring packed cell volume (PCV) is essential to safeguard oxygen delivery to the tissues during cardiopulmonary bypass (CPB). We compared the results obtained using a PCV monitor, a blood gas analyser and a microcentrifuge with those from a laboratory-based automated blood cell counter. PCV was measured in 221 samples of 40 patients undergoing open-heart surgery. The limits of agreement (mean difference +/- 2 SD) was unacceptably wide when the results obtained with the PCV monitor and the blood gas analyser were compared with those of the automated blood cell counter. This was most pronounced when PCV was measured in low concentration samples. The microcentrifuge showed good limits of agreement regardless of sample concentration. The data suggests that measurement of PCV by either continuous monitoring or by a blood gas analyser is not an accurate alternative to an established laboratory method. The microcentrifuge is the most accurate method of the ones investigated to measure haematocrit during CPB.

摘要

在体外循环(CPB)期间监测红细胞压积(PCV)对于保障向组织输送氧气至关重要。我们将使用PCV监测仪、血气分析仪和微量离心机获得的结果与基于实验室的自动血细胞计数器的结果进行了比较。对40例接受心脏直视手术患者的221份样本进行了PCV测量。当将PCV监测仪和血气分析仪获得的结果与自动血细胞计数器的结果进行比较时,一致性界限(平均差异±2标准差)宽得令人无法接受。当在低浓度样本中测量PCV时,这种情况最为明显。无论样本浓度如何,微量离心机都显示出良好的一致性界限。数据表明,通过连续监测或血气分析仪测量PCV并非既定实验室方法的准确替代方法。在研究的用于测量CPB期间血细胞比容的方法中,微量离心机是最准确的方法。

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