Weatherall M S, Sherry K M
Northern General Hospital Trust, Sheffield, UK.
Clin Lab Haematol. 1997 Sep;19(3):183-6.
An open, single centre study was carried out to evaluate the accuracy of the Spuncrit (Micro Diagnostics, Bethlehem, PA, USA) infra-red analyser which can be used for near-patient testing to measure haematocrit and estimate haemoglobin concentration. The primary comparison was with the Sysmex NE1500 (Tao Medical) analyser situated in the main hospital laboratory. Secondary comparison was with the Ciba Corning 288 (Ciba Corning Diagnostics Ltd, Halstead, UK) blood gas analyser currently used for near-patient testing in the Northern General Hospital. A total of 217 samples from 50 patients was analysed. The Pearson's correlation coefficients for haematocrit and haemoglobin concentration between the Spuncrit and Sysmex NE1500 and between the Spuncrit and Ciba Corning 288 were all close, between 0.85 and 0.92. The method of Bland and Altman was used to assess agreement between the results of the Spuncrit and the Sysmex NE1500. The agreement for haematocrit was good with 2 SD of the Spuncrit results being between -5.66 and +4.42% of the measurement from the Sysmex NE1500. In conclusion, the Spuncrit haematocrit measurement agreed well with results from the central laboratory, but the estimated haemoglobin concentrations agreed less well and three reasons are discussed.
开展了一项开放性单中心研究，以评估Spuncrit（美国宾夕法尼亚州伯利恒市Micro Diagnostics公司）红外分析仪的准确性，该分析仪可用于床旁检测以测量血细胞比容并估算血红蛋白浓度。主要对照是与位于医院主实验室的Sysmex NE1500（陶医疗公司）分析仪进行比较。次要对照是与目前在北方总医院用于床旁检测的Ciba Corning 288（英国哈尔斯特德市Ciba Corning诊断有限公司）血气分析仪进行比较。共分析了来自50名患者的217份样本。Spuncrit与Sysmex NE1500之间以及Spuncrit与Ciba Corning 288之间血细胞比容和血红蛋白浓度的Pearson相关系数均接近，在0.85至0.92之间。采用Bland和Altman方法评估Spuncrit与Sysmex NE1500结果之间的一致性。血细胞比容的一致性良好，Spuncrit结果的标准差在Sysmex NE1500测量值的-5.66%至+4.42%之间。总之，Spuncrit血细胞比容测量结果与中心实验室的结果一致性良好，但估算的血红蛋白浓度一致性较差，并讨论了三个原因。
