Nishiyama S, Takano T, Hidaka Y, Takada K, Iwatani Y, Amino N
Department of Laboratory Medicine, Osaka University Medical School, Suita, Japan.
Endocr J. 1993 Aug;40(4):431-8. doi: 10.1507/endocrj.40.431.
A fifty-year-old woman was admitted to our hospital because of generalized edema, progressive symptoms of fatigue and weakness of ten years' duration. After an uneventful third delivery, 24 years before admission, she could not lactate and developed oligomenorrhea and then amenorrhea. Laboratory evaluation revealed panhypopituitarism and pituitary cell antibodies were positive. Both CT scans and MR images showed empty sella. This case is postpartum hypopituitarism without a preceding history of excessive bleeding and may be autoimmune hypophysitis.
一名50岁女性因全身性水肿、持续10年的进行性疲劳和虚弱症状入院。入院前24年，她在一次顺利的第三次分娩后，无法泌乳，随后出现月经过少，然后闭经。实验室检查显示全垂体功能减退，垂体细胞抗体呈阳性。CT扫描和磁共振成像均显示空蝶鞍。该病例为产后垂体功能减退，无前驱大出血病史，可能是自身免疫性垂体炎。
