Kingston R E, Green M R
Department of Molecular Biology, Massachusetts General Hospital, Boston.
Curr Biol. 1994 Apr 1;4(4):325-32. doi: 10.1016/s0960-9822(00)00071-3.
In recent years, many components involved in promoter-specific transcriptional activation in eukaryotes have been identified and characterized. We argue that a proper understanding of transcriptional activation will require quantitative modeling and we outline some of the considerations that such modeling will need to take into account.
近年来,参与真核生物启动子特异性转录激活的许多元件已被鉴定和表征。我们认为,对转录激活的正确理解需要进行定量建模,并且概述了这种建模需要考虑的一些因素。