Izquierdo M
Departamento de Biología Molecular, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco, Spain.
Chromosoma. 1994 Jun;103(3):193-7. doi: 10.1007/BF00368012.
Ubiquitin genes are found in Drosophila either as a repeat block or as gene fusions with ribosomal proteins. Here is described the location of a new repeat block in the X chromosome that is present in the strain Canton S but absent in Vallecas. There are also two ubiquitin-ribosomal protein fusion genes located at regions 97A of chromosome 3R and 31E of 2L. Using an anti-ubiquitin antibody in Drosophila polytene chromosomes it is shown that ubiquitin is mainly associated with the compact and stabilized structure that forms the bands rather than with the more decondensed and destabilized protein-DNA structure that forms interbands and puffs.
泛素基因在果蝇中以重复块或与核糖体蛋白的基因融合形式存在。本文描述了一个位于X染色体上的新重复块的位置，该重复块存在于Canton S品系中，但在Vallecas品系中不存在。在3R染色体的97A区域和2L染色体的31E区域也有两个泛素-核糖体蛋白融合基因。在果蝇多线染色体中使用抗泛素抗体表明，泛素主要与形成带的紧密和稳定结构相关，而不是与形成带间区和胀泡的更解聚和不稳定的蛋白质-DNA结构相关。
