Rose S, Achkar E, Easley K A
Department of Gastroenterology, Cleveland Clinic Foundation, Ohio 44195.
Dig Dis Sci. 1994 Oct;39(10):2063-8. doi: 10.1007/BF02090351.
Noncardiac chest pain may be a debilitating symptom. The utility of esophageal testing to enhance patient quality of life has been inconclusive. The purpose of this study was to evaluate prospectively the impact of esophageal testing on patient well-being. Fifty-five patients undergoing esophageal testing were available for follow-up. Seventeen (31%) patients were classified in group 1: considered to have the esophagus as a likely etiology because of positive testing; 14 (25%) in group 2: possible contribution of the esophagus to symptoms; and 24 (44%) in group 3: unlikely esophageal etiology with negative testing. Thirty-four patients continued to be symptomatic at follow-up (median 112 days). The change in pain intensity from pretesting to follow-up was significant only for group 3 (P = 0.001). There was a decline in hospital utilization in all three groups. (Emergency room visit P = 0.004 group 1, hospital admissions P = 0.02, group 3). Group 1 and 2 patients tended to miss less work, social functions, and activities. Group 3 continued to stay in bed and avoid normal functions. Nine of 34 (26%) patients who were symptomatic at follow-up identified the esophagus as the source of symptoms. In all, 42% of group 1, 29% of group 2, and 18% of group 3 patients considered the esophagus to be the source of their symptoms. We conclude that esophageal testing does not always prevent the persistence of symptoms and that patients have misperceptions about testing results on follow-up.
非心源性胸痛可能是一种使人衰弱的症状。食管检测对提高患者生活质量的效用尚无定论。本研究的目的是前瞻性评估食管检测对患者健康的影响。55例接受食管检测的患者可供随访。17例(31%)患者被归为第1组:检测结果呈阳性,认为食管很可能是病因;14例(25%)在第2组:食管可能是症状的成因之一;24例(44%)在第3组:检测结果为阴性,食管不太可能是病因。34例患者在随访时仍有症状(中位时间112天)。从检测前到随访时疼痛强度的变化仅在第3组有显著差异(P = 0.001)。三组患者的医院就诊率均有所下降。(第1组急诊就诊P = 0.004,第3组住院P = 0.02)。第1组和第2组患者错过的工作、社交活动和日常活动较少。第3组患者继续卧床,避免正常活动。随访时有症状的34例患者中有9例(26%)认为食管是症状来源。总体而言,第1组42%、第2组29%和第3组18%的患者认为食管是其症状来源。我们得出结论,食管检测并不总能防止症状持续存在,并且患者对随访时的检测结果存在误解。