Suppr超能文献

[肠炎沙门氏菌引起的腰椎椎体骨髓炎]

[Lumbar spondylodiscitis caused by Salmonella enteritidis].

作者信息

Schüler A, Schaumann D, Manns M P, Koch K M

机构信息

Abteilung Gastroenterologie und Hepatologie, Zentrum Innere Medizin der Medizinischen Hochschule Hannover.

出版信息

Dtsch Med Wochenschr. 1994 Oct 14;119(41):1383-7. doi: 10.1055/s-2008-1058849.

Abstract

A 19-year-old boy developed paravertebral muscular pain in the lumbar region after an episode of extremely arduous sporting activity, with fever followed by meningism. The cerebrospinal fluid showed a reactive pleocytosis. Initially, no acute inflammatory changes were present on serum and blood analysis, although the erythrocyte sedimentation rate was moderately increased to 25/60 mm. Pyrexia of up to 38.5 degrees C developed 6 days after admission. Because Borrelia IgM and IgG titres were positive, the diagnosis was at first thought to be atypical borreliosis and the patient was treated with antibiotics. However, after a further episode of fever. Salmonella antibody titres, which had initially been normal, rose to 1: 3200 (Salmonella typhi O and H antigens) and 1: 12800 (Salmonella enteritidis, H antigen). At this stage, the erythrocyte sedimentation rate rose to 86/120 mm and the C-reactive protein to 77 mg/dl. The white cell count remained normal throughout. Blood cultures grew Salmonella enteritidis. Abnormalities on bone scintigraphy were confirmed by CT and MRI scans, showing spondylodiscitis of lumbar vertebrae 1 and 2 with limited osteolysis. The lesion resolved completely on 6 week's treatment with ciprofloxacin (200 mg twice a day intravenously) and conservative supportive treatment. Spondylodiscitis is an uncommon complication of salmonellosis and may occur long after the diarrhoea. Cross reactions with Borrelia flagellin antigens may lead to the wrong diagnosis being made.

摘要

一名19岁男孩在经历一次极其剧烈的体育活动后,腰部椎旁肌肉疼痛,继之发热,随后出现脑膜刺激征。脑脊液显示反应性细胞增多。最初,血清和血液分析未见急性炎症改变,尽管红细胞沉降率中度升高至25/60mm。入院6天后体温高达38.5℃。由于伯氏疏螺旋体IgM和IgG滴度呈阳性,起初诊断为非典型疏螺旋体病,患者接受了抗生素治疗。然而,在又一次发热发作后,最初正常的沙门氏菌抗体滴度升至1:3200(伤寒沙门氏菌O和H抗原)和1:12800(肠炎沙门氏菌H抗原)。此时,红细胞沉降率升至86/120mm,C反应蛋白升至77mg/dl。白细胞计数始终正常。血培养生长出肠炎沙门氏菌。骨闪烁扫描异常经CT和MRI扫描证实,显示第1和第2腰椎椎体椎间盘炎伴有限的骨质溶解。经环丙沙星(每日2次,每次200mg静脉滴注)治疗6周及保守支持治疗后,病变完全消退。椎体椎间盘炎是沙门氏菌病的一种罕见并发症,可能在腹泻后很长时间发生。与伯氏疏螺旋体鞭毛蛋白抗原的交叉反应可能导致错误诊断。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验