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一种改良技术,用于II期非精原细胞性生殖细胞肿瘤保留神经的腹膜后淋巴结清扫术,该技术采用术中测量交感神经纤维电刺激后膀胱颈压力变化。

A modified technique for nerve-sparing retroperitoneal lymph node dissection in stage II nonseminomatous germ cell tumors using intraoperative measurement of bladder neck pressure alterations following sympathetic nerve fiber electrostimulation.

作者信息

Weidner W, Zöller G, Sauerwein D, Fischer C, Hummel G, Kallerhoff M, Ringert R H

机构信息

Department of Urology, University of Göttingen, FRG.

出版信息

Eur Urol. 1994;26(1):67-70. doi: 10.1159/000475345.

Abstract

We present a simplified method for nerve-sparing retroperitoneal lymph node dissection in patients with nonseminomatous testicular cancer. The sympathetic fibers involved in antegrade ejaculation are identified by intraoperative electrostimulation, resulting in an increase of bladder neck closure pressure. This increase is demonstrated by intraoperative monitoring of both the intravesical pressure and the pressure within the bladder neck by a two-channel microtip measuring catheter. 4 patients with stage I and 6 patients with stage II nonseminomatous testicular cancer were operated on with this modified technique. Ejaculation was preserved in all cases. Semen volume ranged from 2.2 to 4.0 ml. Sperm cell count ranged from 2 to 22 x 10(6)/ml with 20-50% motile spermatozoa, except for 2 of the 3 patients who initially presented with preoperative azoospermia following chemotherapy. In 1 of these 3 patients, postoperative semen analyses revealed a recovery of germ cell function demonstrated by oligoasthenozoospermia.

摘要

我们提出了一种用于非精原细胞瘤性睾丸癌患者保留神经的腹膜后淋巴结清扫术的简化方法。通过术中电刺激识别参与顺行射精的交感神经纤维,这会导致膀胱颈闭合压力增加。这种增加通过双通道微尖端测量导管对膀胱内压力和膀胱颈内压力的术中监测得以证实。4例I期和6例II期非精原细胞瘤性睾丸癌患者采用这种改良技术进行了手术。所有病例均保留了射精功能。精液量为2.2至4.0毫升。精子细胞计数为2至22×10⁶/毫升,有20%至50%的活动精子,除了3例最初化疗后术前无精子症的患者中的2例。在这3例患者中的1例中,术后精液分析显示少弱精子症表明生殖细胞功能恢复。

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