Lux G, Hagel J, Bäcker P, Bäcker G, Vogl R, Ruppin H, Domschke S, Domschke W
Department of Medicine A, University of Erlangen-Nuremberg, Germany.
Gut. 1994 Aug;35(8):1026-9. doi: 10.1136/gut.35.8.1026.
In a prospective randomised study, the effect of acupuncture on sham feeding stimulated gastric acid secretion was investigated. In eight healthy volunteers (five men, three women, mean (SEM) age 26.3 (4.7) years) various methods of acupuncture were performed. Apart from the sham procedure, the acupuncture was performed at the classic acupuncture points. Electroacupuncture reduced gastric acid secretion expressed as median (range) significantly during the first 30 minute period to 1.6 (0-5.2) mmol compared with 3.8 (2.3-14.5) mmol (p < 0.05) during control period (sham feeding without acupuncture). Inhibition of gastric acid secretion by electroacupuncture was also significant during the second 30 minute period (0.2 (0-5.6) v 3.6 (0.3-9.1) mmol; p < 0.05) and for peak acid output (0.8 (0.2-5.1) v 7.6 (3.4-12.1) mmol; p < 0.05). Transcutaneous electrical nerve stimulation also resulted in significant reduction of gastric acid secretion during the first 30 minute period (1.0 (0-3.6) mmol v 3.8 (2.3-14.5) mmol; p < 0.05), and peak acid output (3.6 (1.2-12.0) v 7.6 (3.4-12.1) mmol; p < 0.05). The classic needle acupuncture, laser acupuncture, and sham acupuncture had no significant effect on gastric acid secretion. This study shows firstly that in healthy volunteers, only the versions of acupuncture using more pronounced stimulation (electroacupuncture, transcutaneous electrical nerve stimulation), but not those with only mild stimulation of the nerves (classic needle acupuncture, laser acupuncture), and secondly only acupuncture performed at defined points lead to significant reduction in gastric acid secretion.
在一项前瞻性随机研究中，研究了针刺对假饲刺激胃酸分泌的影响。对8名健康志愿者（5名男性，3名女性，平均（标准误）年龄26.3（4.7）岁）进行了各种针刺方法。除了假操作外，针刺在经典穴位进行。电针在最初30分钟内显著降低胃酸分泌，以中位数（范围）表示为1.6（0 - 5.2）mmol，而对照期（无针刺的假饲）为3.8（2.3 - 14.5）mmol（p < 0.05）。电针在第二个30分钟内对胃酸分泌的抑制也很显著（0.2（0 - 5.6）对3.6（0.3 - 9.1）mmol；p < 0.05），对胃酸峰值输出也有显著抑制（0.8（0.2 - 5.1）对7.6（3.4 - 12.1）mmol；p < 0.05）。经皮电神经刺激在最初30分钟内也导致胃酸分泌显著减少（1.0（0 - 3.6）mmol对3.8（2.3 - 14.5）mmol；p < 0.05），以及胃酸峰值输出（3.6（1.2 - 12.0）对7.6（3.4 - 12.1）mmol；p < 0.05）。经典针刺、激光针刺和假针刺对胃酸分泌无显著影响。这项研究首先表明，在健康志愿者中，只有使用更强烈刺激的针刺方式（电针、经皮电神经刺激）能显著减少胃酸分泌，而仅轻微刺激神经的方式（经典针刺、激光针刺）则不能；其次，只有在特定穴位进行针刺才会导致胃酸分泌显著减少。
