Sakuma H, Kikuta A, Suzuki H
Department of Pediatrics, Fukushima Medical College, Japan.
Fukushima J Med Sci. 1993 Dec;39(2):113-6.
In this paper, we summarize methods of treatment of graft versus host disease (GVHD) after allo bone marrow transplantation (BMT) with drugs, which could be applied to the treatment of GVHD after blood transfusion. Corticosteroid, ATG, and cyclosporine have generally been used for the treatment of GVHD after allo BMT. Some of the immunosuppressive drugs, which are newly developed, are useful too. In future, anti-TNF alpha antibodies and anti-IL6 antibodies could be effective in patients with GVHD.
在本文中,我们总结了使用药物治疗异基因骨髓移植(BMT)后移植物抗宿主病(GVHD)的方法,这些方法可应用于输血后GVHD的治疗。皮质类固醇、抗胸腺细胞球蛋白(ATG)和环孢素通常用于治疗异基因BMT后的GVHD。一些新开发的免疫抑制药物也很有用。未来,抗TNFα抗体和抗IL6抗体可能对GVHD患者有效。