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白色念珠菌溶血因子的产生。

Production of a hemolytic factor by Candida albicans.

作者信息

Manns J M, Mosser D M, Buckley H R

机构信息

Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.

出版信息

Infect Immun. 1994 Nov;62(11):5154-6. doi: 10.1128/iai.62.11.5154-5156.1994.

DOI:10.1128/iai.62.11.5154-5156.1994
PMID:7927798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC303238/
Abstract

Candida albicans exhibits hemolytic activity when grown on glucose-enriched blood agar. This activity is present on intact organisms, and it is secreted into the culture medium. Hemoglobin released from lysed erythrocytes can restore the transferrin-inhibited growth of C. albicans. We conclude that C. albicans expresses a hemolytic factor which allows it to acquire iron from host erythrocytes.

摘要

白色念珠菌在富含葡萄糖的血琼脂上生长时表现出溶血活性。这种活性存在于完整的生物体上，并分泌到培养基中。从裂解的红细胞中释放的血红蛋白可以恢复转铁蛋白抑制的白色念珠菌生长。我们得出结论，白色念珠菌表达一种溶血因子，使其能够从宿主红细胞中获取铁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d16/303238/1f0b7218c9d6/iai00011-0471-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d16/303238/3c120f6ef72c/iai00011-0471-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d16/303238/1f0b7218c9d6/iai00011-0471-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d16/303238/3c120f6ef72c/iai00011-0471-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d16/303238/1f0b7218c9d6/iai00011-0471-b.jpg

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