Hafner H, Pratt H, Blazer S, Sujov P
Evoked Potentials Laboratory, Technion-Israel Institute of Technology, Haifa, Israel.
Hear Res. 1994 Jun 1;76(1-2):7-15. doi: 10.1016/0378-5955(94)90082-5.
This study compared intra- and extra-uterine maturation of the auditory pathway, using auditory brainstem evoked potentials (ABEPs), recorded with three orthogonal differential electrode configurations. From the three records of each subject, 3-channel Lissajous' trajectories (3CLTs) were derived and analyzed. 107 newborns were compared at the same gestational and post-conceptional (gestational+postnatal) age, from 29 weeks (wks) up to 43 wks. In addition, we explored the effects and neurophysiological consequences of early exposure to extra-uterine life, on the peripheral and central portions of the auditory pathway. Our findings indicate that exposure of premature infants to the extra-uterine environment is associated with advanced peripheral development, but slower central conduction compared to intra-uterine development.
本研究采用听觉脑干诱发电位（ABEP），通过三种正交差分电极配置进行记录，比较了听觉通路在子宫内和子宫外的成熟情况。从每个受试者的三次记录中得出并分析了三通道李萨如轨迹（3CLT）。对107名新生儿在相同孕周和受孕后（孕周+出生后）年龄进行了比较，年龄范围从29周（wk）到43周。此外，我们探讨了早期暴露于子宫外环境对听觉通路外周和中枢部分的影响及神经生理学后果。我们的研究结果表明，与子宫内发育相比，早产儿暴露于子宫外环境与外周发育提前有关，但中枢传导较慢。
