Nicolle L E
Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.
J Antimicrob Chemother. 1994 May;33 Suppl A:99-109. doi: 10.1093/jac/33.suppl_a.99.
Urinary infection is very common in elderly populations. Infection is usually asymptomatic, and there is currently no indication for the treatment of asymptomatic bacteriuria except before invasive genitourinary procedures. For symptomatic infection the goal of treatment is relief of symptoms, not sterilization of the urine. The choice of antimicrobial for treatment of symptomatic infection will be determined by considerations similar to younger populations. Elderly women presenting with lower urinary tract symptoms are less likely to be cured by antibiotics, particularly short courses of therapy, than younger women. Many aspects of urinary infection in the elderly require further study, including assessment of the impact of morbidity, comparative studies of antimicrobial agents, determination of optimal durations of therapy, and defining situations in which urological investigation will improve patient outcome.
尿路感染在老年人群中非常常见。感染通常无症状,目前除了在进行侵入性泌尿生殖系统操作之前,没有治疗无症状菌尿的指征。对于有症状的感染,治疗目标是缓解症状,而非使尿液无菌。治疗有症状感染时抗菌药物的选择将由与年轻人群类似的因素决定。与年轻女性相比,出现下尿路症状的老年女性用抗生素治愈的可能性较小,尤其是短疗程治疗。老年人尿路感染的许多方面都需要进一步研究,包括发病率影响的评估、抗菌药物的比较研究、确定最佳治疗疗程以及明确哪些情况下泌尿外科检查会改善患者预后。