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tolC和rfa突变对大肠杆菌K-12外膜疏水屏障的累加效应。

Additive effect of tolC and rfa mutations on the hydrophobic barrier of the outer membrane of Escherichia coli K-12.

作者信息

Fralick J A, Burns-Keliher L L

机构信息

Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock 79430.

出版信息

J Bacteriol. 1994 Oct;176(20):6404-6. doi: 10.1128/jb.176.20.6404-6406.1994.

Abstract

Studies using tolC mutant derivatives of deep rough (rfa) mutants indicate that tolC and rfa mutations have an additive effect with respect to their sensitivity to hydrophobic agents, suggesting that they are not acting through a mutual mechanism to alter the permeability of the outer membrane.

摘要

使用深粗糙型(rfa)突变体的tolC突变体衍生物进行的研究表明,tolC和rfa突变在对疏水性试剂的敏感性方面具有累加效应,这表明它们并非通过共同机制来改变外膜的通透性。

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