Bauer S M
Rush University, College of Nursing, Chicago, Illinois.
J Adv Nurs. 1994 Jun;19(6):1114-20. doi: 10.1111/j.1365-2648.1994.tb01195.x.
The new field of psychoneuroimmunology (PNI) studies the measurable interaction between psychological and physiological processes. Specifically, PNI is the study of the intricate interaction of consciousness (psycho), central nervous system (neuro), and the body's defense against external infection and aberrant cell division (immunology). Over the last 30 years, the body of knowledge in PNI has emerged and in the last 10 years has flourished. PNI has many implications for clinical nursing practice. This study provides supportive empirical evidence to systems theories, which have played a major role in nursing's attempt to comprehend the interaction between the mind and the body. Nurses are ideal candidates to take a lead in this new field because it reinforces the holistic perspective which is the essence and uniqueness of our discipline. Although a variety of clinical populations have been used in PNI research, the scope of this integrated review will be limited to PNI and cancer. Research studies addressing psychosocial variables' effect on aetiology, response to treatment, immunocompetence and overall survival in the oncology population will be examined.
心理神经免疫学（PNI）这一新兴领域研究心理与生理过程之间可测量的相互作用。具体而言，PNI研究意识（心理）、中枢神经系统（神经）以及身体抵御外部感染和异常细胞分裂（免疫学）之间的复杂相互作用。在过去30年里，PNI领域的知识体系逐渐形成，并在过去10年蓬勃发展。PNI对临床护理实践有诸多影响。本研究为系统理论提供了支持性实证依据，这些理论在护理界试图理解身心相互作用的过程中发挥了重要作用。护士是引领这一新兴领域的理想人选，因为它强化了整体观，而整体观正是我们学科的本质和独特之处。尽管PNI研究中使用了各种临床人群，但本整合综述的范围将限于PNI与癌症。将对探讨心理社会变量对肿瘤患者病因、治疗反应、免疫能力和总体生存影响的研究进行审查。
