Schapiro J M, Shpitzer S, Pinkhas J, Sidi Y, Arber N
Department of Medicine D, Beilinson Medical Center, Israel.
J Med. 1994;25(1-2):121-8.
Takayasu's arteritis is a chronic inflammatory arteriopathy of unknown cause. The pulseless phase of Takayasu's arteritis is preceded by a period of "prepulseless disease" when the patients suffer from systematic symptoms without obvious evidence of obstruction of larger arteries. Herein we report a unique case of Takayasu's arteritis presenting as sarcoidosis manifested by restrictive lung disease, hilar adenopathy and non-caseating granulomas of the skin. We are aware of only one report in which non-caseating skin granulomas were evident at the prepulseless phase of Takayasu's arteritis. However, in our patient the clinical picture was typical of sarcoidosis. Increased awareness of this possibility will lead to more frequent skin biopsies in patients with Takayasu's arteritis and nodular skin lesions, which may increase the number of reported cases with this combination.
高安动脉炎是一种病因不明的慢性炎症性动脉病。高安动脉炎的无脉期之前有一段“无脉前期疾病”时期，此时患者出现全身症状，但无明显的大动脉阻塞证据。在此，我们报告一例独特的高安动脉炎病例，其表现为结节病，表现为限制性肺病、肺门淋巴结肿大和皮肤非干酪样肉芽肿。我们仅知晓一份报告，其中在高安动脉炎的无脉前期出现了明显的非干酪样皮肤肉芽肿。然而，我们的患者临床表现为典型的结节病。提高对这种可能性的认识将导致高安动脉炎和结节性皮肤病变患者更频繁地进行皮肤活检，这可能会增加这种组合的报告病例数。
