Structure and antimicrobial activity of diterpenes from the roots of Plectranthus hereroensis.
作者信息
Batista O, Duarte A, Nascimento J, Simões M F, de la Torre M C, Rodríguez B
机构信息
Faculdade de Farmácia de Lisboa, Universidade de Lisboa, Portugal.
出版信息
J Nat Prod. 1994 Jun;57(6):858-61. doi: 10.1021/np50108a031.
PMID:7931371
Abstract
Two abietane-type diterpenoids have been isolated from the roots of Plectranthus hereroensis (Labiatae), one being the already known horminone [1] and the other a new substance, 7 alpha,12-dihydroxy-17(15-->16)-abeo-abieta-8,12,16-triene-11 ,14-dione [2], whose structure was established by spectroscopic means. Compounds 1 and 2 showed antimicrobial activity against Staphylococcus aureus, Vibrio cholerae, Candida albicans, and Pseudomonas aeruginosa.
摘要
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