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Structure and antimicrobial activity of diterpenes from the roots of Plectranthus hereroensis.

作者信息

Batista O, Duarte A, Nascimento J, Simões M F, de la Torre M C, Rodríguez B

机构信息

Faculdade de Farmácia de Lisboa, Universidade de Lisboa, Portugal.

出版信息

J Nat Prod. 1994 Jun;57(6):858-61. doi: 10.1021/np50108a031.

DOI:10.1021/np50108a031
PMID:7931371
Abstract

Two abietane-type diterpenoids have been isolated from the roots of Plectranthus hereroensis (Labiatae), one being the already known horminone [1] and the other a new substance, 7 alpha,12-dihydroxy-17(15-->16)-abeo-abieta-8,12,16-triene-11 ,14-dione [2], whose structure was established by spectroscopic means. Compounds 1 and 2 showed antimicrobial activity against Staphylococcus aureus, Vibrio cholerae, Candida albicans, and Pseudomonas aeruginosa.

摘要

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