Litke D S, Dahners L E
Department of Orthopaedic Surgery, University of South Carolina School of Medicine, Columbia.
J Orthop Res. 1994 Sep;12(5):683-8. doi: 10.1002/jor.1100120511.
Electrical stimulation has been shown to enhance the repair of biological tissues such as bone and tendon. The objective of this study was to determine whether low level direct current enhances the early healing of injured medial collateral ligaments. Eighty-seven rats were divided into three groups on the basis of the level of current delivered. All underwent transection of the medial collateral ligament bilaterally. The experimental medial collateral ligaments received current (which varied by group), while the contralateral medial collateral ligaments (the controls), with identical electrodes, received no current. After 12 days, each ligament was tested biomechanically with use of a hydraulic materials testing machine. Group 1 (8.6 +/- 5.9 microA) showed statistically significant improvements in maximum rupture force, energy absorbed, stiffness, and laxity. The groups that had received lower levels of current did not show significant improvements. In this study, stimulation of 1-20 microA was the most effective level of direct current for the enhancement of early healing of the medial collateral ligament.
电刺激已被证明可促进诸如骨骼和肌腱等生物组织的修复。本研究的目的是确定低强度直流电是否能促进内侧副韧带损伤的早期愈合。根据施加电流的水平，将87只大鼠分为三组。所有大鼠均双侧切断内侧副韧带。实验侧的内侧副韧带接受电流（电流因组而异），而对侧的内侧副韧带（对照组）使用相同电极但不接受电流。12天后，使用液压材料试验机对每条韧带进行生物力学测试。第1组（8.6±5.9微安）在最大断裂力、能量吸收、刚度和松弛度方面显示出统计学上的显著改善。接受较低电流水平的组未显示出显著改善。在本研究中，1-20微安的刺激是促进内侧副韧带早期愈合的最有效直流电水平。
