皮下注射后，高锝酸盐从水/油微乳液和水溶液中的释放情况（家兔实验）

Pertechnetate release from a water/oil microemulsion and an aqueous solution after subcutaneous injection in rabbits.

作者信息

Bellò M, Colangelo D, Gasco M R, Maranetto F, Morel S, Podio V, Turco G L, Viano I

机构信息

Cattedra di Medicina Nucleare, Facoltà di Medicina, Torino, Italy.

出版信息

J Pharm Pharmacol. 1994 Jun;46(6):508-10. doi: 10.1111/j.2042-7158.1994.tb03837.x.

DOI:10.1111/j.2042-7158.1994.tb03837.x

PMID:7932049

Abstract

A water-oil microemulsion and an aqueous solution, both carrying pertechnetate, were injected subcutaneously in rabbits; release was observed by imaging the administration sites with a gamma-camera. Disappearance from the injection site of pertechnetate in aqueous solution was about ten times faster than that of pertechnetate in a microemulsion.

摘要

将携带高锝酸盐的水包油微乳液和水溶液皮下注射到兔子体内；通过使用γ相机对给药部位进行成像来观察释放情况。水溶液中高锝酸盐从注射部位的消失速度比微乳液中高锝酸盐快约十倍。