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妊娠期严重出血性膀胱炎的管理:两例报告

Management of severe hemorrhagic cystitis in pregnancy. A report of two cases.

作者信息

Fakhoury G F, Daikoku N H, Parikh A R

机构信息

Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

J Reprod Med. 1994 Jun;39(6):485-8.

PMID:7932406
Abstract

Acute hemorrhagic cystitis (AHC) is gross hematuria and symptoms of cystitis. Usually a self-limiting entity, it is found mainly in children and cancer patients receiving chemotherapy or radiation. In a small number of patients, AHC can be severe and require aggressive management. We present two cases of severe acute hemorrhagic cystitis in pregnant women that led to hemorrhage, resistance to antibiotic therapy and premature labor. Continuous bladder irrigation with normal saline was attempted with success in stopping the hematuria and arresting the premature labor. Severe hemorrhagic cystitis in pregnancy may require aggressive management when associated with a significant blood loss and preterm labor.

摘要

急性出血性膀胱炎(AHC)表现为肉眼血尿和膀胱炎症状。它通常是一种自限性疾病,主要见于儿童以及接受化疗或放疗的癌症患者。在少数患者中,AHC可能较为严重,需要积极治疗。我们报告了两例孕妇严重急性出血性膀胱炎病例,这两例病例导致了出血、对抗生素治疗耐药以及早产。尝试用生理盐水持续膀胱冲洗,成功止住了血尿并抑制了早产。妊娠合并严重出血性膀胱炎,若伴有大量失血和早产,可能需要积极治疗。

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