Greenberg R A, Strecher V J, Bauman K E, Boat B W, Fowler M G, Keyes L L, Denny F W, Chapman R S, Stedman H C, LaVange L M
Department of Pediatrics, School of Medicine, University of North Carolina, Chapel Hill 27514.
J Behav Med. 1994 Jun;17(3):273-90. doi: 10.1007/BF01857953.
We conducted a randomized controlled trial to determine whether a home-based intervention program could reduce infant passive smoking and lower respiratory illness. The intervention consisted of four nurse home visits during the first 6 months of life, designed to assist families to reduce the infant's exposure to tobacco smoke. Among the 121 infants of smoking mothers who completed the study, there was a significant difference in trend over the year between the intervention and the control groups in the amount of exposure to tobacco smoke; infants in the intervention group were exposed to 5.9 fewer cigarettes per day at 12 months. There was no group difference in infant urine cotinine excretion. The prevalence of persistent lower respiratory symptoms was lower among intervention-group infants of smoking mothers whose head of household had no education beyond high school: intervention group, 14.6%; and controls, 34.0%.
我们进行了一项随机对照试验,以确定一项家庭干预计划是否能够减少婴儿被动吸烟并降低下呼吸道疾病的发生率。干预措施包括在婴儿出生后的前6个月内进行4次护士家访,旨在帮助家庭减少婴儿接触烟草烟雾的机会。在完成研究的121名母亲吸烟的婴儿中,干预组和对照组在一年中接触烟草烟雾的量的变化趋势存在显著差异;干预组的婴儿在12个月时每天接触的香烟数量减少了5.9支。两组婴儿尿中可替宁排泄量没有差异。在户主仅受过高中以下教育的吸烟母亲的干预组婴儿中,持续性下呼吸道症状的发生率较低:干预组为14.6%,对照组为34.0%。