Petersen T, Just-Christensen J E, Kousgaard P, Holmboe B, Klemar B
Neurological Department, University Hospital of Aarhus, Denmark.
J Urol. 1994 Nov;152(5 Pt 1):1460-2. doi: 10.1016/s0022-5347(17)32445-x.
Evaluation of maximal electrical sphincter stimulation in 13 patients with detrusor hyperreflexia showed no change in volume at first or duration of hyperreflexia, or bladder capacity during a stimulation period of 4 times 30 minutes, when compared single blind to a similar registration without sphincter stimulation. After 12 days of stimulation 30 minutes twice daily, 10 of 12 patients reported improvement in irritative bladder symptoms but no significant changes were seen in the cystometric findings and only 2 patients wanted to continue treatment. The anal plug stimulator had 4 separate electrodes, 1 stimulating at a time. Despite this, significant fatigue of the sphincter activity was measured after the stimulation period. In conclusion, we found that the efficacy of sphincter stimulation in patients with detrusor hyperreflexia and irritative bladder symptoms was limited.
对13例逼尿肌反射亢进患者进行最大电括约肌刺激评估，结果显示，在4次每次30分钟的刺激期内，与单盲对照的无括约肌刺激的类似记录相比，首次出现逼尿肌反射亢进时的尿量、反射亢进持续时间或膀胱容量均无变化。在每天两次、每次30分钟的刺激12天后，12例患者中有10例报告膀胱刺激症状有所改善，但膀胱测压结果未见显著变化，只有2例患者希望继续治疗。肛门塞刺激器有4个独立电极，每次1个电极进行刺激。尽管如此，在刺激期后仍测得括约肌活动有明显疲劳。总之，我们发现括约肌刺激对逼尿肌反射亢进和膀胱刺激症状患者的疗效有限。
