Kohira I, Matsuo E, Shiro Y, Uemura N, Matsumoto S, Kitamura Y, Matsumoto Y, Ishizu H, Sakai K, Kuroda S
Department of Neurology, Okayama University Medical School, Japan.
Jpn J Psychiatry Neurol. 1994 Mar;48(1):33-6. doi: 10.1111/j.1440-1819.1994.tb02993.x.
A case of hepatic encephalopathy with increased cerebral blood flow in single-photon emission computed tomography (SPECT) and abnormalities upon magnetic resonance imaging (MRI) is reported. SPECT showed increased blood flow exceeding 70 ml/100 g/min in the cerebellum, basal ganglia and cerebral cortex, with hyperammonemia and abnormal electroencephalographic signs showing severe generalized slowing. SPECT data and MRI might reflect abnormal metabolism and neuropathological changes in hepatic encephalopathy.