Meyer J H, Soriano J M, Janknecht P, Funk J
Universitäts-Augenklinik Freiburg.
Klin Monbl Augenheilkd. 1994 Jul;205(1):14-8. doi: 10.1055/s-2008-1045484.
The success of a cyclocryocogulation is not only defined by the reduction of the intraocular pressure but also by the simplification of the therapy necessary for the regulation of the glaucoma.
We examined retrospectively the charts of 27 patients with glaucoma chronicum simplex (GCS) and 63 patients with various types of non-simplex glaucomas (NGCS). All underwent a cyclocryocoagulation made 51 seconds at -70 to -80 degrees C, 4 mm behind the limbus at 6 points.
IOP was controlled (i.e. < 25 mm Hg and decreased > 20% of the preoperative value) in 69% of the cases (GCS 70%, NGCS 68%) 3-5 days after the operation. IOP decreased from 31 to 19 mm Hg on average. The effect decreased with time, more than 12 months after the operation only 36% of the eyes were still regulated. 4 eyes with persisting pain had to be enucleated. The cyclocryocoagulation never caused blindness or phthisis bulbi. Therapy with eye drops was necessary in 70% of the patients preoperatively, and in 37% postoperatively. Oral carboanhydrase inhibitors had to be used in 57% of the patients before and in 20% of the cases after the operation.
Cyclocryocoagulation is considered an effective method to lower IOP and simplify drug therapy without having serious complications.
睫状体冷凝术的成功不仅取决于眼压的降低，还在于简化青光眼治疗所需的疗法。
我们回顾性研究了27例单纯性慢性青光眼（GCS）患者和63例各种类型非单纯性青光眼（NGCS）患者的病历。所有患者均在角膜缘后4mm处6个点进行了-70至-80摄氏度、持续51秒的睫状体冷凝术。
术后3至5天，69%的病例眼压得到控制（即眼压<25mmHg且较术前值降低>20%）（GCS为70%，NGCS为68%）。眼压平均从31mmHg降至19mmHg。随着时间推移效果下降，术后12个月以上仅有36%的眼睛眼压仍得到控制。4例持续疼痛的眼睛不得不摘除眼球。睫状体冷凝术从未导致失明或眼球痨。术前70%的患者需要使用眼药水治疗，术后这一比例为37%。术前57%的患者必须使用口服碳酸酐酶抑制剂，术后这一比例为20%。
睫状体冷凝术被认为是一种降低眼压并简化药物治疗且无严重并发症的有效方法。
