Bleckmann H
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1976 Nov 18;201(1):69-77. doi: 10.1007/BF00410149.
Dichlorphenamide as well as Diamox lowers intraocular pressure. For adequate treatment of acute glaucoma only 20% of commonly used Diamoxdosis is requested to reach comparable pressure release two hours later. After one hour control intraocular pressure of 60% from patients with Dichlorphenamide treatment was found below 40 mm Hg since in Diamoxgroup there were only 30% below 40 mm Hg. Different effects of Dichlorphenamide and Diamox after one hour use is demonstrated in respect of serum electrolytes and base excess as well. Essential side effects after a single dosis of 200 mg Dichlorphenamide or in combination with Diamox for acute glaucoma treatment could not be observed.
双氯非那胺以及醋氮酰胺均可降低眼压。对于急性青光眼的充分治疗，仅需常用醋氮酰胺剂量的20%即可在两小时后达到相当的眼压降低效果。双氯非那胺治疗组中，60%的患者在用药一小时后眼压控制在40 mmHg以下，而醋氮酰胺组仅有30%的患者眼压低于40 mmHg。双氯非那胺和醋氮酰胺在使用一小时后对血清电解质和碱剩余也有不同影响。在急性青光眼治疗中，单次服用200 mg双氯非那胺或与醋氮酰胺联合使用时，未观察到明显的副作用。
