Wallner I, Hartmann H, Ramadori G
Medizinische Universitätsklinik Göttingen, Abteilung Gastroenterologie und Endokrinologie.
Leber Magen Darm. 1994 Jul;24(4):150, 153-4.
Hepatocellular carcinoma (HCC) is the most frequent primary malignancy of the liver, most prevalent in Asia and Africa but also showing a rising incidence worldwide. Chronic hepatitis B and C virus infection is the most important risk factor for HCC. More than half of the patients suffer from underlying liver cirrhosis. The prognosis is determined by tumor stage and residual capacity of the liver, the median survival being 0.9 to 12.8 months for patients receiving no specific treatment. In the East, early detection has been improved by screening programs which seem to be less valuable in the Western world.
肝细胞癌（HCC）是最常见的原发性肝癌，在亚洲和非洲最为普遍，但在全球范围内发病率也呈上升趋势。慢性乙型和丙型肝炎病毒感染是HCC最重要的危险因素。超过一半的患者患有潜在的肝硬化。预后取决于肿瘤分期和肝脏的剩余功能，未接受特异性治疗的患者中位生存期为0.9至12.8个月。在东方，筛查项目改善了早期检测，而在西方世界，这些项目似乎价值不大。
