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[吡喹酮治疗华支睾吸虫病自然疫源地的经验]

[Treatment experience with biltricide in a natural focus of opisthorchiasis].

作者信息

Guzeeva T M, Kliuchnikov S I, Iagodina L A, Starova N E

出版信息

Med Parazitol (Mosk). 1994 Apr-Jun(2):53.

PMID:7935193
Abstract

Since 1992, a total of 72 opisthorchiasis patients have been treated with biltricide in the outpatient setting, with laboratory pre-examination of their blood organs. The treatment was made in a course dose of 60 mg/kg body weight during a day. On the following day the patients underwent duodenal probing to remove parasites. Adverse reactions as giddiness were noted in 9 patients. The efficiency of the therapy was monitored 3 months later, the control analysis detected no Opisthorchis eggs in 96% of the patients. The outpatient use of bilthricide indicates its high efficiency in the treatment of opisthorchiasis if the following requirements are met: preparation of patients, drug taking in the presence of a medical worker.

摘要

自1992年以来,共有72例华支睾吸虫病患者在门诊接受了吡喹酮治疗,并对其血液器官进行了实验室预检查。治疗采用每日60mg/kg体重的疗程剂量。次日,患者接受十二指肠探查以清除寄生虫。9例患者出现头晕等不良反应。3个月后监测治疗效果,对照分析发现96%的患者未检测到华支睾吸虫卵。如果满足以下要求,门诊使用吡喹酮表明其在治疗华支睾吸虫病方面具有很高的疗效:患者的准备工作、在医务人员在场的情况下服药。

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