紫外线和焦油在戈克曼银屑病治疗法中的应用

Ultraviolet light and tar in the Goeckerman treatment of psoriasis.

作者信息

Marsico A R, Eaglstein W H, Weinstein G D

出版信息

Arch Dermatol. 1976 Sep;112(9):1249-50.

Abstract

In an attempt to evaluate and improve the Goeckerman treatment of psoriasis, combinations of tar and ultraviolet (UV) light were studied. The effects of UV irradiation alone, of curde coal tar (CCT) ointment alone, and of UV irradiation with 1% CCT ointment and with 6% CCT ointment on psoriatic lesions were compared. The combinations of 1% CCT ointment with UV irradiation and of 6% CCT ointment with UV irradiation were found to be equally effective. The combination of UV irradiation with ointment had little effect on psoriatic lesions. In most cases, the combination of 1% CCT ointment and UV irradiation was superior to high-concentration (6%) tar ointment without UV irradiation. This study suggests that UV light is an important component of the Goeckerman treatment ant that tar and UV irradiation are superior to tar alone.

摘要

为了评估和改进戈克曼银屑病疗法，对焦油与紫外线（UV）光的联合使用进行了研究。比较了单独紫外线照射、单独粗制煤焦油（CCT）软膏以及1%CCT软膏和6%CCT软膏与紫外线照射对银屑病皮损的影响。发现1%CCT软膏与紫外线照射的联合以及6%CCT软膏与紫外线照射的联合效果相同。紫外线照射与软膏联合对银屑病皮损影响不大。在大多数情况下，1%CCT软膏与紫外线照射的联合优于未进行紫外线照射的高浓度（6%）焦油软膏。这项研究表明，紫外线光是戈克曼疗法的一个重要组成部分，并且焦油与紫外线照射联合优于单独使用焦油。