Asanza L, Rao G, Voleti C, Hartstein M L, Wisoff B G
Ann Thorac Surg. 1976 Dec;22(6):532-4. doi: 10.1016/s0003-4975(10)64471-2.
A controlled clinical study was carried out to decide whether the pericardium should be left open or closed after open-heart operations. One hundred patients had the pericardium closed with interrupted silk, another 100 had the pericardium left open. Complications were alike except for the more frequent occurrence of a pericardial rub in the closed group (14 vs 3 patients), though the incidence of post-pericardiotomy syndrome was equal. There was no late tamponade. Two early reexplorations for bleeding were done in the open group, none in the closed. There were no postoperative deaths. In the patients who consented to postoperative angiography following revascularization procedures, the incidence of graft failure was equal in both groups. The pericardium should be closed after an open-heart operation. Morbidity and mortality are unchanged, and repeat cardiac exploration is safer.
开展了一项对照临床研究,以确定心脏直视手术后心包应开放还是闭合。100例患者的心包用间断丝线缝合闭合,另外100例患者的心包保持开放。除了闭合组心包摩擦音更频繁出现(14例对3例患者)外,两组并发症相似,尽管心包切开术后综合征的发生率相同。没有发生晚期心脏压塞。开放组有2例因出血进行早期再次探查,闭合组无。无术后死亡病例。在同意血管重建术后进行术后血管造影的患者中,两组移植失败的发生率相同。心脏直视手术后心包应闭合。发病率和死亡率未变,再次心脏探查更安全。