一种缺少氨基酸重复序列的重组克氏锥虫转唾液酸酶保留了酶活性。 - Suppr

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超能文献

A recombinant Trypanosoma cruzi trans-sialidase lacking the amino acid repeats retains the enzymatic activity.

作者信息

Campetella O E, Uttaro A D, Parodi A J, Frasch A C

机构信息

Instituto de Investigaciones Bioquímicas, Fundación Campomar, Buenos Aires, Argentina.

出版信息

Mol Biochem Parasitol. 1994 Apr;64(2):337-40. doi: 10.1016/0166-6851(94)00036-0.

DOI:10.1016/0166-6851(94)00036-0

PMID:7935611

Abstract

摘要

相似文献

A recombinant Trypanosoma cruzi trans-sialidase lacking the amino acid repeats retains the enzymatic activity.一种缺少氨基酸重复序列的重组克氏锥虫转唾液酸酶保留了酶活性。

Mol Biochem Parasitol. 1994 Apr;64(2):337-40. doi: 10.1016/0166-6851(94)00036-0.

Members of the SAPA/trans-sialidase protein family have identical N-terminal sequences and a putative signal peptide.唾液酸酶激活蛋白/转唾液酸酶蛋白家族的成员具有相同的N端序列和一个假定的信号肽。

Mol Biochem Parasitol. 1993 May;59(1):171-4. doi: 10.1016/0166-6851(93)90018-s.

The complete sequence of a shed acute-phase antigen of Trypanosoma cruzi.克氏锥虫脱落急性期抗原的完整序列。

Mol Biochem Parasitol. 1991 Aug;47(2):247-50. doi: 10.1016/0166-6851(91)90185-9.

Trans-sialidase, SAPA amino acid repeats and the relationship between Trypanosoma cruzi and the mammalian host.转唾液酸酶、南美锥虫表面糖蛋白氨基酸重复序列以及克氏锥虫与哺乳动物宿主之间的关系。

Parasitology. 1994;108 Suppl:S37-44. doi: 10.1017/s0031182000075703.

Endothelial cell signalling induced by trans-sialidase from Trypanosoma cruzi.克氏锥虫转唾液酸酶诱导的内皮细胞信号传导

Cell Microbiol. 2008 Jan;10(1):88-99. doi: 10.1111/j.1462-5822.2007.01017.x. Epub 2007 Aug 2.

Trypanosoma cruzi trans-sialidase gene lacking C-terminal repeats and expressed in epimastigote forms.克氏锥虫转唾液酸酶基因，缺乏C末端重复序列并以无鞭毛体形式表达。

Mol Biochem Parasitol. 1995 Mar;70(1-2):9-17. doi: 10.1016/0166-6851(95)00004-k.

Isolation and characterization of the TSA/trans-sialidase family gene from the Silvio strain of Trypanosoma cruzi.从克氏锥虫西尔维奥菌株中分离和鉴定TSA/转唾液酸酶家族基因

Mol Biochem Parasitol. 1993 Nov;62(1):117-20. doi: 10.1016/0166-6851(93)90184-y.

SA85-1 proteins of Trypanosoma cruzi lack sialidase activity.克氏锥虫的SA85-1蛋白缺乏唾液酸酶活性。

Mol Biochem Parasitol. 1993 Jul;60(1):149-52. doi: 10.1016/0166-6851(93)90038-y.

The repetitive domain of Trypanosoma cruzi trans-sialidase enhances the immune response against the catalytic domain.克氏锥虫转唾液酸酶的重复结构域增强了针对催化结构域的免疫反应。

J Infect Dis. 1998 Feb;177(2):431-6. doi: 10.1086/514199.

Molecular cloning of the gene encoding the 83 kDa amastigote surface protein and its identification as a member of the Trypanosoma cruzi sialidase superfamily.编码83 kDa无鞭毛体表面蛋白的基因的分子克隆及其作为克氏锥虫唾液酸酶超家族成员的鉴定。

Mol Biochem Parasitol. 1997 Sep;88(1-2):137-49. doi: 10.1016/s0166-6851(97)00088-1.

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Parasite-host glycan interactions during Trypanosoma cruzi infection: trans-Sialidase rides the show.寄生虫-宿主糖基相互作用在克氏锥虫感染期间：转涎酶领衔主演。

Biochim Biophys Acta Mol Basis Dis. 2020 May 1;1866(5):165692. doi: 10.1016/j.bbadis.2020.165692. Epub 2020 Jan 20.

Modulation of Cell Sialoglycophenotype: A Stylish Mechanism Adopted by Trypanosoma cruzi to Ensure Its Persistence in the Infected Host.细胞唾液酸糖表型的调控：克氏锥虫采用的一种巧妙机制，以确保其在受感染宿主中的持续存在。

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Rab11 regulates trafficking of trans-sialidase to the plasma membrane through the contractile vacuole complex of Trypanosoma cruzi.Rab11通过克氏锥虫的收缩泡复合体调节转唾液酸酶向质膜的运输。

PLoS Pathog. 2014 Jun 26;10(6):e1004224. doi: 10.1371/journal.ppat.1004224. eCollection 2014 Jun.

Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.克氏锥虫 trans-sialidase 启动了一个独立于转录因子 RORγt 和 Ahr 的程序，导致激活的 B 细胞产生 IL-17。

Nat Immunol. 2013 May;14(5):514-22. doi: 10.1038/ni.2569. Epub 2013 Apr 7.

Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation.鉴定克氏锥虫转涎糖基酶（一种扰乱淋巴细胞糖基化的毒力因子）的糖蛋白靶标。

Glycobiology. 2010 Jul;20(7):833-42. doi: 10.1093/glycob/cwq037. Epub 2010 Mar 30.

Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex.克氏锥虫感染中胸腺细胞耗竭是由转唾液酸酶诱导的滋养细胞复合体凋亡介导的。

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3896-901. doi: 10.1073/pnas.052496399. Epub 2002 Mar 12.

Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.克氏锥虫转唾液酸酶的表位作图揭示了几种交叉反应性决定簇的存在。

Infect Immun. 2001 Mar;69(3):1869-75. doi: 10.1128/IAI.69.3.1869-1875.2001.

trans-sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease.转唾液酸酶抑制试验，一种用于恰加斯病的高度敏感且特异的诊断测试。

Clin Diagn Lab Immunol. 2001 Jan;8(1):187-9. doi: 10.1128/CDLI.8.1.187-189.2001.

Use of trans-Sialidase inhibition assay in a population serologically negative for Trypanosoma cruzi but at a high risk of infection.在血清学检测为克氏锥虫阴性但感染风险高的人群中使用转唾液酸酶抑制试验。

Clin Diagn Lab Immunol. 1998 Mar;5(2):254-5. doi: 10.1128/CDLI.5.2.254-255.1998.

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