• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Use of trans-Sialidase inhibition assay in a population serologically negative for Trypanosoma cruzi but at a high risk of infection.在血清学检测为克氏锥虫阴性但感染风险高的人群中使用转唾液酸酶抑制试验。
Clin Diagn Lab Immunol. 1998 Mar;5(2):254-5. doi: 10.1128/CDLI.5.2.254-255.1998.
2
Diagnostic Applicability of Neutralizing Antibodies to Trypanosoma cruzi Trans-sialidase.针对克氏锥虫转唾液酸酶的中和抗体的诊断适用性
Methods Mol Biol. 2019;1955:239-246. doi: 10.1007/978-1-4939-9148-8_18.
3
Trans-sialidase inhibition assay for the detection of Trypanosoma cruzi infection in blood donor samples from Argentina.用于检测阿根廷献血者样本中克氏锥虫感染的转涎酶抑制检测。
Vox Sang. 2008 Oct;95(3):189-96. doi: 10.1111/j.1423-0410.2008.01088.x.
4
Trans-sialidase inhibition assay detects Trypanosoma cruzi infection in different wild mammal species.转唾液酸酶抑制试验可检测不同野生哺乳动物物种中的克氏锥虫感染。
Vector Borne Zoonotic Dis. 2013 Aug;13(8):581-5. doi: 10.1089/vbz.2012.1125. Epub 2013 May 13.
5
Estimation of sensitivity and specificity of several Trypanosoma cruzi antibody assays in blood donors in Argentina.在阿根廷，对几种用于献血者的克氏锥虫抗体检测方法的敏感性和特异性的评估。
Transfusion. 2009 Nov;49(11):2352-8. doi: 10.1111/j.1537-2995.2009.02301.x.
6
Virulence Factors for the Diagnosis of Chagas' Disease.用于诊断恰加斯病的毒力因子。
ACS Infect Dis. 2019 Nov 8;5(11):1813-1819. doi: 10.1021/acsinfecdis.9b00269. Epub 2019 Sep 24.
7
Long-lasting antibodies detected by a trans-sialidase inhibition assay of sera from parasite-free, serologically cured chagasic patients.通过对无寄生虫、血清学治愈的恰加斯病患者血清进行转唾液酸酶抑制试验检测到的持久抗体。
J Infect Dis. 1997 May;175(5):1272-5. doi: 10.1086/593697.
8
[Reactivity of GST-SAPA antigen of Trypanosoma cruzi against sera from patients with Chagas disease and leishmaniasis].[克氏锥虫谷胱甘肽 S-转移酶-南美锥虫抗原对恰加斯病和利什曼病患者血清的反应性]
Medicina (B Aires). 2011;71(2):113-9.
9
Antibodies inhibiting Trypanosoma cruzi trans-sialidase activity in sera from human infections.抑制人类感染血清中克氏锥虫转唾液酸酶活性的抗体。
J Infect Dis. 1994 Dec;170(6):1570-4. doi: 10.1093/infdis/170.6.1570.
10
Performance of different Trypanosoma cruzi antigens in the diagnosis of Chagas disease in patients with American cutaneous leishmaniasis from a co-endemic region in Argentina.不同克氏锥虫抗原在阿根廷一地方性流行区感染美洲皮肤利什曼病的恰加斯病患者诊断中的表现。
Trop Med Int Health. 2013 Sep;18(9):1103-1109. doi: 10.1111/tmi.12144. Epub 2013 Jul 10.

引用本文的文献

1
Parasite-host glycan interactions during Trypanosoma cruzi infection: trans-Sialidase rides the show.寄生虫-宿主糖基相互作用在克氏锥虫感染期间：转涎酶领衔主演。
Biochim Biophys Acta Mol Basis Dis. 2020 May 1;1866(5):165692. doi: 10.1016/j.bbadis.2020.165692. Epub 2020 Jan 20.
2
Next-generation ELISA diagnostic assay for Chagas Disease based on the combination of short peptidic epitopes.基于短肽表位组合的恰加斯病下一代酶联免疫吸附诊断检测法。
PLoS Negl Trop Dis. 2017 Oct 9;11(10):e0005972. doi: 10.1371/journal.pntd.0005972. eCollection 2017 Oct.
3
Trans-sialidase inhibition assay detects Trypanosoma cruzi infection in different wild mammal species.转唾液酸酶抑制试验可检测不同野生哺乳动物物种中的克氏锥虫感染。
Vector Borne Zoonotic Dis. 2013 Aug;13(8):581-5. doi: 10.1089/vbz.2012.1125. Epub 2013 May 13.
4
trans-Sialidase neutralizing antibody detection in Trypanosoma cruzi-infected domestic reservoirs.在克氏锥虫感染的家栖宿主中检测转唾液酸酶中和抗体
Clin Vaccine Immunol. 2011 Jun;18(6):984-9. doi: 10.1128/CVI.00535-10. Epub 2011 Apr 6.
5
Estimation of sensitivity and specificity of several Trypanosoma cruzi antibody assays in blood donors in Argentina.在阿根廷，对几种用于献血者的克氏锥虫抗体检测方法的敏感性和特异性的评估。
Transfusion. 2009 Nov;49(11):2352-8. doi: 10.1111/j.1537-2995.2009.02301.x.
6
Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas' disease after drug treatment.使用克氏锥虫重组转唾液酸酶的酶联免疫吸附测定可用于监测接受药物治疗后的恰加斯病患者。
Clin Diagn Lab Immunol. 2003 Sep;10(5):826-30. doi: 10.1128/cdli.10.5.826-830.2003.
7
Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex.克氏锥虫感染中胸腺细胞耗竭是由转唾液酸酶诱导的滋养细胞复合体凋亡介导的。
Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3896-901. doi: 10.1073/pnas.052496399. Epub 2002 Mar 12.
8
Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.克氏锥虫转唾液酸酶的表位作图揭示了几种交叉反应性决定簇的存在。
Infect Immun. 2001 Mar;69(3):1869-75. doi: 10.1128/IAI.69.3.1869-1875.2001.
9
trans-sialidase inhibition assay, a highly sensitive and specific diagnostic test for Chagas' disease.转唾液酸酶抑制试验，一种用于恰加斯病的高度敏感且特异的诊断测试。
Clin Diagn Lab Immunol. 2001 Jan;8(1):187-9. doi: 10.1128/CDLI.8.1.187-189.2001.

本文引用的文献

1
Long-lasting antibodies detected by a trans-sialidase inhibition assay of sera from parasite-free, serologically cured chagasic patients.通过对无寄生虫、血清学治愈的恰加斯病患者血清进行转唾液酸酶抑制试验检测到的持久抗体。
J Infect Dis. 1997 May;175(5):1272-5. doi: 10.1086/593697.
2
Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi.克氏锥虫重组转唾液酸酶的中规模生产及纯化至均一性
Cell Mol Biol (Noisy-le-grand). 1996 Jul;42(5):703-10.
3
Detection of Trypanosoma cruzi in blood specimens of chronic chagasic patients by polymerase chain reaction amplification of kinetoplast minicircle DNA: comparison with serology and xenodiagnosis.通过动基体小环DNA的聚合酶链反应扩增检测慢性恰加斯病患者血液标本中的克氏锥虫：与血清学和虫媒接种诊断法的比较
J Clin Microbiol. 1993 Sep;31(9):2421-6. doi: 10.1128/jcm.31.9.2421-2426.1993.
4
Mice infected with Trypanosoma cruzi produce antibodies against the enzymatic domain of trans-sialidase that inhibit its activity.感染克氏锥虫的小鼠会产生针对转唾液酸酶酶结构域的抗体，这些抗体可抑制其活性。
Infect Immun. 1994 Aug;62(8):3441-6. doi: 10.1128/iai.62.8.3441-3446.1994.
5
Sera from chronic Chagasic patients and rodents infected with Trypanosoma cruzi inhibit trans-sialidase by recognizing its amino-terminal and catalytic domain.来自慢性恰加斯病患者和感染克氏锥虫的啮齿动物的血清通过识别其氨基末端和催化结构域来抑制转唾液酸酶。
Infect Immun. 1994 Jul;62(7):2973-8. doi: 10.1128/iai.62.7.2973-2978.1994.
6
Antibodies inhibiting Trypanosoma cruzi trans-sialidase activity in sera from human infections.抑制人类感染血清中克氏锥虫转唾液酸酶活性的抗体。
J Infect Dis. 1994 Dec;170(6):1570-4. doi: 10.1093/infdis/170.6.1570.
7
A recombinant Trypanosoma cruzi trans-sialidase lacking the amino acid repeats retains the enzymatic activity.一种缺少氨基酸重复序列的重组克氏锥虫转唾液酸酶保留了酶活性。
Mol Biochem Parasitol. 1994 Apr;64(2):337-40. doi: 10.1016/0166-6851(94)00036-0.
8
Immunoassay with recombinant Trypanosoma cruzi antigens potentially useful for screening donated blood and diagnosing Chagas disease.使用重组克氏锥虫抗原进行免疫测定，可能有助于筛查献血和诊断恰加斯病。
Clin Chem. 1994 Oct;40(10):1893-7.
9
High correlation between Chagas' disease serology and PCR-based detection of Trypanosoma cruzi kinetoplast DNA in Bolivian children living in an endemic area.在生活于流行地区的玻利维亚儿童中，恰加斯病血清学与基于聚合酶链反应检测克氏锥虫动基体DNA之间存在高度相关性。
FEMS Microbiol Lett. 1994 Dec 15;124(3):419-23. doi: 10.1111/j.1574-6968.1994.tb07318.x.
10
Structural and functional properties of Trypanosoma trans-sialidase.锥虫转唾液酸酶的结构与功能特性
Annu Rev Microbiol. 1994;48:499-523. doi: 10.1146/annurev.mi.48.100194.002435.

在血清学检测为克氏锥虫阴性但感染风险高的人群中使用转唾液酸酶抑制试验。

Use of trans-Sialidase inhibition assay in a population serologically negative for Trypanosoma cruzi but at a high risk of infection.

作者信息

Leguizamón M S, Russomando G, Rojas de Arias A, Samudio M, Cabral M, González-Cappa S M, Frasch A C, Campetella O

机构信息

Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Paraguay.

出版信息

Clin Diagn Lab Immunol. 1998 Mar;5(2):254-5. doi: 10.1128/CDLI.5.2.254-255.1998.

DOI:10.1128/CDLI.5.2.254-255.1998
PMID:9521153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC121368/
Abstract

trans-Sialidase inhibition assay (TIA) was employed in a population at high risk of Trypanosoma cruzi infection. From 20 serum samples that were negative by conventional serologic and parasitologic assays, 18 (90%) were reactive in TIA, providing further evidence of the higher sensitivity of TIA and suggesting that the actual prevalence of T. cruzi infection might be underestimated.

摘要

转唾液酸酶抑制试验（TIA）应用于克氏锥虫感染高危人群。在20份经传统血清学和寄生虫学检测呈阴性的血清样本中，18份（90%）在TIA中呈反应性，这进一步证明了TIA具有更高的敏感性，并表明克氏锥虫感染的实际患病率可能被低估。