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加拿大和美国急性心肌梗死后医疗资源的使用及生活质量

Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States.

作者信息

Mark D B, Naylor C D, Hlatky M A, Califf R M, Topol E J, Granger C B, Knight J D, Nelson C L, Lee K L, Clapp-Channing N E

机构信息

Duke University Medical Center, Durham, NC 27708-3485.

出版信息

N Engl J Med. 1994 Oct 27;331(17):1130-5. doi: 10.1056/NEJM199410273311706.

Abstract

BACKGROUND

Much attention has been directed to the use of medical resources and to patients' outcomes in Canada as compared with the United States. We compared U.S. and Canadian patients with respect to their use of medical resources and their quality of life during the year after acute myocardial infarction.

METHODS

A total of 2600 U.S. and 400 Canadian patients were randomly selected from the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO) trial. Base-line data from their initial hospitalizations were analyzed, and the patients were then interviewed by telephone 30 days, 6 months, and 1 year after myocardial infarction to determine their use of medical care and quality of life.

RESULTS

The Canadian patients typically stayed in the hospital one day longer (P = 0.009) than the U.S. patients but had a much lower rate of cardiac catheterization (25 percent vs. 72 percent, P < 0.001), coronary angioplasty (11 percent vs. 29 percent, P < 0.001), and coronary bypass surgery (3 percent vs. 14 percent, P < 0.001). At one year 24 percent of the Canadian and 53 percent of the U.S. patients had undergone angioplasty or bypass surgery at least once (P < 0.001). The Canadian had more visits to physicians during the follow-up year (P < 0.001), but fewer visits to specialists (P < 0.001). At 30 days, functional status was equivalent in the patients from the two countries. However, after one year the U.S. patients had substantially more improvement than the Canadian patients (P < 0.001). The prevalence of chest pain and dyspnea at one year was higher among the Canadian patients (34 percent vs. 21 percent and 45 percent vs. 29 percent, respectively; P < 0.001).

CONCLUSIONS

The Canadian patients had more cardiac symptoms and worse functional status one year after acute myocardial infarction than the U.S. patients. The Canadian patients also underwent fewer invasive cardiac procedures and had fewer visits to specialist physicians. These results suggest, but do not prove, that the more aggressive pattern of care in the United States may have been responsible for the better quality of life.

摘要

背景

与美国相比,加拿大在医疗资源使用和患者治疗结果方面备受关注。我们比较了美国和加拿大急性心肌梗死后一年患者的医疗资源使用情况和生活质量。

方法

从冠状动脉闭塞使用链激酶和组织型纤溶酶原激活剂的全球应用(GUSTO)试验中随机选取2600名美国患者和400名加拿大患者。分析他们首次住院的基线数据,然后在心肌梗死后30天、6个月和1年通过电话采访患者,以确定他们的医疗护理使用情况和生活质量。

结果

加拿大患者的住院时间通常比美国患者长一天(P = 0.009),但心脏导管插入术(25%对72%,P < 0.001)、冠状动脉血管成形术(11%对29%,P < 0.001)和冠状动脉搭桥手术(3%对14%,P < 0.001)的发生率低得多。一年后,24%的加拿大患者和53%的美国患者至少接受过一次血管成形术或搭桥手术(P < 0.001)。加拿大患者在随访年度内看医生的次数更多(P < 0.001),但看专科医生的次数较少(P < 0.001)。在30天时,两国患者的功能状态相当。然而,一年后,美国患者的改善程度明显高于加拿大患者(P < 0.001)。一年时加拿大患者胸痛和呼吸困难的发生率更高(分别为34%对21%和45%对29%;P < 0.001)。

结论

急性心肌梗死后一年,加拿大患者比美国患者有更多的心脏症状和更差的功能状态。加拿大患者接受的侵入性心脏手术也较少,看专科医生的次数也较少。这些结果表明,但未证明,美国更积极的治疗模式可能是生活质量较好的原因。

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