原位肝移植相关感染：一项着重于移植物相关败血症的研究。
Infections complicating orthotopic liver transplantation: a study emphasizing graft-related septicemia.
作者信息
Schröter G P, Hoelscher M, Putnam C W, Porter K A, Hansbrough J F, Starzl T E
出版信息
Arch Surg. 1976 Dec;111(12):1337-47. doi: 10.1001/archsurg.1976.01360300027004.
Abstract
In 93 recipients of 102 orthotopic liver homografts, the incidence of bacteremia or fungemia exceeded 70%. The graft itself was usually an entry site for systemic infection after both immunologic and nonimmunologic parenchymal injury, especially if there was defective biliary drainage. The role of the homograft itself as the special infectious risk factor has prompted increased use of defunctionalized jejunal Roux limbs to reduce graft contamination. It has also stimulated very aggressive postoperative diagnostic efforts to rule out remedial mechanical complications of the transplant.
摘要
在102例原位肝同种移植的93例受者中，菌血症或真菌血症的发生率超过70%。在免疫性和非免疫性实质损伤后，移植物本身通常是全身感染的入口部位，尤其是在胆汁引流存在缺陷的情况下。同种移植物本身作为特殊感染危险因素的作用促使人们更多地使用去功能化的空肠Roux袢来减少移植物污染。这也激发了术后非常积极的诊断努力，以排除移植的补救性机械并发症。
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