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肛周克罗恩病

Perianal Crohn's disease.

作者信息

ten Cate Hoedemaker H O

机构信息

Department of Surgery, Groningen University Hospital, Netherlands.

出版信息

Neth J Med. 1994 Aug;45(2):72-5.

PMID:7936009
Abstract

Perianal disease in Crohn's disease is a difficult matter to deal with. The indication for therapy is not always clear in this disease with a relatively mild natural course. More confusion is caused by the fact that not all disease in the perianal region in a patient with Crohn's has to be Crohn-related. The usual ailments such as haemorrhoids may occur in a patient with Crohn's disease. The treatment has to be as for every patient. Primary mucosal and submucosal Crohn's disease in the anal canal has to be treated like uncomplicated Crohn's disease in the rest of the gastrointestinal tract with appropriate medication. The option for therapy in complicated abdominal Crohn's disease, most often resection, is not available in perianal disease without giving up faecal continence. One has to make a compromise, wishing to treat the disease as radically as possible, while preserving faecal continence as much as possible. The basis for treatment for complicated Crohn's disease is medical treatment for the primary disease. The choice in surgical options depends on the type of complication. A different strategy is needed for each type of complication. The therapy is different for perianal abscesses, rectovaginal fistulas, stenosis, high perianal fistulas and low perianal fistulas. It is proposed to treat abscesses by early incision and drainage, rectovaginal fistulas by a mucosal advancement anoplasty, high perianal fistulas by a seton procedure, low perianal fistulas by fistulotomy, and stenosis by mild dilatation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

克罗恩病中的肛周疾病是一个难以处理的问题。在这种自然病程相对较轻的疾病中,治疗指征并不总是明确的。更令人困惑的是,克罗恩病患者肛周区域的所有疾病并非都与克罗恩病相关。克罗恩病患者可能会出现诸如痔疮等常见病症。治疗必须因人而异。肛管原发性黏膜和黏膜下克罗恩病必须像治疗胃肠道其他部位的非复杂性克罗恩病一样,使用适当的药物进行治疗。在不放弃大便失禁的情况下,复杂腹部克罗恩病最常用的治疗方法即切除手术,在肛周疾病中并不适用。人们必须做出妥协,既要尽可能彻底地治疗疾病,又要尽可能保留大便失禁功能。复杂克罗恩病的治疗基础是针对原发性疾病的药物治疗。手术选择取决于并发症的类型。每种并发症都需要不同的策略。肛周脓肿、直肠阴道瘘、狭窄、高位肛周瘘和低位肛周瘘的治疗方法各不相同。建议通过早期切开引流治疗脓肿,通过黏膜推进肛门成形术治疗直肠阴道瘘,通过挂线疗法治疗高位肛周瘘,通过瘘管切开术治疗低位肛周瘘,通过轻度扩张治疗狭窄。(摘要截选于250字)

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