Sumida M, Uozumi T, Yamanaka M, Mukada K, Arita K, Kurisu K, Satoh H, Ikawa F
Department of Neurosurgery, Hiroshima University School of Medicine, Japan.
Neuroradiology. 1994 Jul;36(5):372-5. doi: 10.1007/BF00612121.
We compared the position of the normal pituitary gland as estimated by gadolinium (Gd)-DTPA-enhanced MRI, with its position at surgery in 40 patients with intra- and juxtasellar tumours: 22 pituitary adenomas, 4 craniopharyngiomas, 7 meningiomas, 2 germinomas, and 5 Rathke cleft cysts. In 37 of these, the normal gland showed more intense contrast enhancement than the adjacent tumour, from which it could be differentiated by Gd-DTPA-enhanced MRI, especially in the sagittal plane. The direction of displacement of the normal pituitary gland correlated well with tumour type, so that its position proved helpful in the differential diagnosis. The normal gland was typically displaced superiorly by pituitary adenomas, inferiorly by craniopharyngiomas, and anteriorly by germinomas. It showed variable displacement by Rathke cleft cysts, and was not usually displaced by meningiomas.
我们比较了40例鞍内和鞍旁肿瘤患者中钆（Gd）-二乙三胺五乙酸（DTPA）增强磁共振成像（MRI）所估计的正常垂体位置与其手术时的位置，这些肿瘤包括：22例垂体腺瘤、4例颅咽管瘤、7例脑膜瘤、2例生殖细胞瘤和5例拉克氏囊肿。其中37例中，正常垂体腺比相邻肿瘤显示出更强的对比增强，通过Gd-DTPA增强MRI可将其与肿瘤区分开来，尤其是在矢状面上。正常垂体腺的移位方向与肿瘤类型密切相关，因此其位置有助于鉴别诊断。垂体腺瘤通常使正常垂体腺向上移位，颅咽管瘤使其向下移位，生殖细胞瘤使其向前移位。拉克氏囊肿使其移位情况不一，脑膜瘤通常不使其移位。
