蛋白质结构-序列比对的HSSP数据库。
The HSSP database of protein structure-sequence alignments.
作者信息
Sander C, Schneider R
机构信息
Protein Design Group, European Molecular Biology Laboratory, Heidelberg, Germany.
出版信息
Nucleic Acids Res. 1994 Sep;22(17):3597-9.
Abstract
HSSP (homology-derived structures of proteins) is a derived database merging structural (2-D and 3-D) and sequence information (1-D). For each protein of known 3D structure from the Protein Data Bank, the database has a file with all sequence homologues, properly aligned to the PDB protein. Homologues are very likely to have the same 3D structure as the PDB protein to which they have been aligned. As a result, the database is not only a database of sequence aligned sequence families, but it is also a database of implied secondary and tertiary structures.
摘要
HSSP（蛋白质同源衍生结构）是一个合并了结构（二维和三维）和序列信息（一维）的衍生数据库。对于蛋白质数据库中每个已知三维结构的蛋白质，该数据库都有一个包含所有序列同源物的文件，这些同源物已与PDB蛋白质正确比对。同源物很可能具有与其比对的PDB蛋白质相同的三维结构。因此，该数据库不仅是一个比对序列家族的数据库，也是一个隐含二级和三级结构的数据库。
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