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匙叶黄杨保肝活性的研究。 (注:Gymnosporia montana常见中文名匙叶黄杨 ,这里按照常见中文名翻译,原英文标题可能有误,推测实际研究对象应该是匙叶黄杨的相关活性,而不是Gymnosporia montana这个属的保肝活性,因为Gymnosporia montana是植物分类学上的一个种,一般不会说它有保肝活性,而是其提取物或成分有保肝活性等,这里先按字面翻译并指出可能存在的问题供你参考。 )

An investigation on the hepatoprotective activity of Gymnosporia montana.

作者信息

De S, Ravishankar B, Bhavsar G C

机构信息

Institute of Post-Graduate Teaching and Research, Gujarat Ayurved University, Dhanvantari Mandir, Jamnagar, India.

出版信息

Planta Med. 1994 Aug;60(4):301-4. doi: 10.1055/s-2006-959488.

Abstract

The methanol extract of the defatted leaves of Gymnosporia montana was evaluated for hepatoprotective activity by noting its effect on carbon tetrachloride (CCl4)-induced changes in liver cytoarchitecture and alterations in certain biochemical parameters. The main parameters studied were transaminase activity, lipid constituents of serum and liver, orosomucoid level in serum, and liver glycogen and phospholipid contents. The extract administration led to a significant reversal of the majority of the altered biochemical parameters. Besides, a significant antagonism of the CCl4-induced changes in the liver cytoarchitecture was also observed. The results confirm the presence of hepatoprotective activity in the plant material.

摘要

通过观察其对四氯化碳(CCl₄)诱导的肝脏细胞结构变化和某些生化参数改变的影响,对山地裸实脱脂叶的甲醇提取物进行了保肝活性评估。研究的主要参数包括转氨酶活性、血清和肝脏的脂质成分、血清中类粘蛋白水平以及肝脏糖原和磷脂含量。提取物给药导致大多数改变的生化参数显著逆转。此外,还观察到对CCl₄诱导的肝脏细胞结构变化有显著拮抗作用。结果证实了该植物材料中存在保肝活性。

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