Rajesh M G, Latha M S
School of Biosciences, Mahatma Gandhi University, PD Hills P. O., Kottayam-686 560.
Indian J Physiol Pharmacol. 2001 Oct;45(4):481-6.
The efficacy of the medicinal plant Elephantopus scaber Linn. (Asteraceae), to prevent carbon teterachloride (CCI4)-induced chronic liver dysfunction in the rats was examined by determining different biochemical markers in serum and tissues. In serum, liver function marker enzymes like aspartate aminotrasferase (AST), alanine aminotrasferase (ALT), alkaline phosphatase (ALP) and also protein were evaluated. The concentrations of total lipid, cholesterol and phospholipids were studied in serum and the different tissues. The concentration of serum triglycerides was also studied. The biochemical changes induced by CCI4 in different tissues particularly in the liver tissue improved following treatment with E. scaber Linn. The results suggest the hepatoprotective effect of this medicinal plant.
通过测定大鼠血清和组织中的不同生化标志物，研究了药用植物地胆草（菊科）预防四氯化碳（CCl4）诱导的大鼠慢性肝功能障碍的功效。在血清中，评估了肝功能标志物酶，如天冬氨酸转氨酶（AST）、丙氨酸转氨酶（ALT）、碱性磷酸酶（ALP）以及蛋白质。研究了血清和不同组织中总脂质、胆固醇和磷脂的浓度。还研究了血清甘油三酯的浓度。用四氯化碳处理不同组织尤其是肝组织后所诱导的生化变化，在用地胆草治疗后得到改善。结果表明这种药用植物具有保肝作用。
