Janaszek W
Zakład Badania Surowic i Szczepionek Państwowego Zakładu Higieny w Warszawie.
Przegl Epidemiol. 1994;48(3):285-92.
Three freeze-dried BCG vaccines: Polish, Danish and Japan were compared. It was found, that they fullfill all WHO requirements for freeze-dried BCG vaccine. They were shown to have a high survival of bacilli upon freeze-drying, good viability, thermostability and allergizing properties in guinea pigs. Japan BCG vaccine had especially high viability and thermostability. Mentioned BCG vaccines were safe for guinea pigs even in dose of 5 mg BCG (100 human doses) administrated subcutaneously. It was shown, that Polish BCG vaccine, that is regarded as vaccine of middle strength does not differ essentialy from strong Danish vaccine in respect to viability, thermostability and allergizing properties in guinea pigs evaluated 6 weeks after vaccination.
波兰的、丹麦的和日本的进行了比较。结果发现，它们均符合世界卫生组织对冻干卡介苗的所有要求。冻干时它们显示出高菌苗存活率，在豚鼠体内具有良好的活力、热稳定性和致敏特性。日本卡介苗尤其具有高活力和热稳定性。上述卡介苗对豚鼠是安全的，即使皮下注射5毫克卡介苗（100人用剂量）。结果表明，被视为中等强度疫苗的波兰卡介苗，在接种6周后评估的豚鼠活力、热稳定性和致敏特性方面，与强的丹麦疫苗并无本质差异。
