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疟疾中的贫血和血小板减少症。II. 在格但斯克海洋与热带医学研究所诊所观察的45例疟疾患者的平均红细胞和血小板计数

[Anemia and thrombocytopenia in malaria. II. Mean erythrocyte and thrombocyte count in 45 patients with malaria observed in the Clinic of the Institute of Maritime and Tropical Medicine in Gdynia].

作者信息

Górski J, Nahorski W, Goljan J, Felczak-Korzybska I, Myjak P

机构信息

Klinika Chorób Zawodowych i Tropikalnych Instytutu Medycyny Morskiej i Tropikalnej, Gdynia.

出版信息

Przegl Lek. 1994;51(6):243-5.

PMID:7938658
Abstract

In the years 1987-92, 45 patients with malaria were hospitalized in our clinic. All the patients were before staying in tropical countries. 30 patients were infected with PI. falciparum while the rest - with other species of this parasite. From among numerous different symptoms of malaria, in the majority of the patients profound anaemia and thrombocytopenia occurred. The simultaneously observed drop in the erythrocyte and blood platelet levels confirms that the destruction pathways of them in patients with malaria may be similar, as are the reasons for ineffective erythro- and thrombocytopoiesis. Anaemia and thrombocytopenia gradually subsided in the course of the therapy, as the parasitemia decreased and the state of the patients improved.

摘要

在1987年至1992年期间,45例疟疾患者在我们诊所住院。所有患者此前都曾在热带国家停留。30例患者感染恶性疟原虫,其余患者感染该寄生虫的其他种类。在疟疾众多不同症状中,大多数患者出现了严重贫血和血小板减少。同时观察到的红细胞和血小板水平下降证实,疟疾患者中它们的破坏途径可能相似,红细胞生成和血小板生成无效的原因也相似。随着治疗过程中疟原虫血症减少且患者状况改善,贫血和血小板减少逐渐消退。

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